Evidence map›Paper›PMID 41822162›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2019

Multi-x-ray source array for stationary tomosynthesis or multi-cone angle cone beam CT.

John M Boone, Amy E Becker, Andrew M Hernandez, James T Dobbins, Paul Schwoebel

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

John M BooneDepartment of Radiology, University of California Davis.
Amy E BeckerDepartment of Radiology, University of California Davis.
Andrew M HernandezDepartment of Radiology, University of California Davis.
James T DobbinsSRI International and Department of Physics, University of New Mexico Albuquerque.
Paul SchwoebelSRI International and Department of Physics, University of New Mexico Albuquerque.

Funding

A Prototype Stationary X-Ray Source Digital Breast Tomosynthesis SystemR01CA214515 · NCI · UNIVERSITY OF NEW MEXICO · PI SCHWOEBEL, PAUL R · 2017 to 2025
$3.1M
Breast CT: Final Steps to TranslationR01CA181081 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BOONE, JOHN M · 2015 to 2019
$2.9M
NCI NIH HHS R01 CA181081NCI NIH HHS R01 CA214515
6 · The paper itself

Abstract

Field-emission x-ray source arrays have been studied for both tomosynthesis and CT applications, however these arrays tend to have limited output. We propose the use of multi-source x-ray arrays using thermionic cathodes, contained within a single vacuum housing. A prototype 3-source x-ray array has been fabricated and tested, and the utility of multi-x-ray-source arrays has been demonstrated using physical simulations in both tomosynthesis and in cone beam CT. The prototype x-ray tube made use of a cylindrical molybdenum anode, machined to have 3 specific focal tracks. Grid-controlled cathode assemblies were fabricated and aligned to each focal tract, and the individual x-ray focal spots were evaluated with a star pattern at 35 kV and 40 mA. The 3-source assembly was used to physically simulate tomosynthesis imaging geometry, and tomosynthesis images of a lemon were obtained. Physical simulations using a cone beam breast CT scanner were also performed, by vertically moving the single x-ray source into 5 different locations - simulating 5 different source positions. A new geometry for cone beam CT imaging is proposed, where each source of a multi-x-ray source array is individually collimated to eliminate rays involving large cone angles. This geometry also allows three sources to be simultaneously pulsed onto a single flat panel detector, achieving better duty cycle and view sampling in cone beam CT. A reconstruction algorithm was written to accommodate the different source positions, and phantoms designed to demonstrate cone beam artifacts were imaged. The tomosynthesis images illustrate appropriate depth resolution in the test object. Analysis of the CT data demonstrate marked improvement compared to one source. We conclude that multi-source x-ray arrays using thermionic cathodes will have important applications in medical imaging, especially breast tomosynthesis and cone beam computed tomography.

Identifiers

PMID41822162
PMCPMC12978392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.