Evidence map›Paper›PMID 41822092›Full record

SynthesisFrontiers in gastroenterology (Lausanne, Switzerland)2022

A systematic review and meta-analysis of

Anthony Carona, David Jacobson, Charles F Hildebolt, Waqar Qureshi, Kevin C Rowland

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in gastroenterology (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anthony CaronaDepartment of Biomedical Sciences, Tilman J. Fertitta Family College of Medicine, University of Houston, Houston, United States.
David JacobsonDepartment of Biomedical Sciences, Tilman J. Fertitta Family College of Medicine, University of Houston, Houston, United States.
Charles F HildeboltDepartment of Radiology, Washington University School of Medicine, St. Louis, United States.
Waqar QureshiDivision of Gastroenterology, Baylor College of Medicine, Houston, United States.
Kevin C RowlandDepartment of Biomedical Sciences, Tilman J. Fertitta Family College of Medicine, University of Houston, Houston, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Probiotics are widely used and prescribed to address a host of health issues. Despite evidence that different probiotic bacteria have differing therapeutic mechanisms of action, many probiotics are prescribed indiscriminately, with little research to support the use of specific formulations for a given ailment. Further investigation is required to assess the efficacy of one commonly prescribed probiotic formulation Methods: A systematic search of randomized placebo-controlled trials evaluating the effectiveness of combination Results: Analyses revealed the overall proportion of cases with diarrhea in the treatment group, 36 participants who had diarrhea out of 91 total, was only 3.5% lower than the overall proportion in the placebo group, 44 participants who had diarrhea out of 105 total.(P = 0.508), with our considering that the 3.5 lower percentage to be of little or no clinical importance. Conclusion: Existing literature suggests little or no clinical benefit of a

Indexed as

antibiotic associated diarrhealactinexlactobacillus acidophilusLactobacillus bulgaricusprobioticstravelers’ diarrhea

Identifiers

PMID41822092
PMCPMC12952393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.