Evidence map›Paper›PMID 41822086›Full record

ArticleFrontiers in gastroenterology (Lausanne, Switzerland)2022

Change of Left Ventricular Myocardial Contractility in Speckle Tracking Echocardiography After Transjugular Intrahepatic Portosystemic Shunt Predicts Survival.

Christian Jansen, Pia Nordmann, Carla Cremonese, Michael Praktiknjo, Johannes Chang, Jennifer Lehmann, Daniel Thomas, Georg Nickenig, Marcel Weber, Elisabeth Stöhr and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in gastroenterology (Lausanne, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Christian JansenDepartment of Internal Medicine I, University of Bonn, Bonn, Germany.
Pia NordmannDepartment of Internal Medicine I, University of Bonn, Bonn, Germany.
Carla CremoneseMedical Department I, Goethe University Clinic Frankfurt, Frankfurt, Germany.
Michael PraktiknjoDepartment of Internal Medicine I, University of Bonn, Bonn, Germany.
Johannes ChangDepartment of Internal Medicine I, University of Bonn, Bonn, Germany.
Jennifer LehmannDepartment of Internal Medicine I, University of Bonn, Bonn, Germany.
Daniel ThomasDepartment of Radiology, University Clinic Bonn, Bonn, Germany.
Georg NickenigDepartment of Internal Medicine II, University Clinic Bonn, Bonn, Germany.
Marcel WeberDepartment of Internal Medicine II, University Clinic Bonn, Bonn, Germany.
Elisabeth StöhrDepartment of Internal Medicine II, University Clinic Bonn, Bonn, Germany.
Can ÖztürkDepartment of Internal Medicine II, University Clinic Bonn, Bonn, Germany.
Christian ZachovalDepartment of Internal Medicine II, University Clinic Bonn, Bonn, Germany.
Christoph HammerstinglDepartment of Internal Medicine II, University Clinic Bonn, Bonn, Germany.
Christian P StrassburgDepartment of Internal Medicine I, University of Bonn, Bonn, Germany.
Carsten MeyerDepartment of Radiology, University Clinic Bonn, Bonn, Germany.
Jonel TrebickaEuropean Foundation for Study of Chronic Liver Failure, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Left ventricular global longitudinal strain (LV-GLS) has been shown to better reflect the left cardiac contractility in cirrhosis than other investigations and might bear prognostic value. The aim of this study was to investigate the evolution of myocardial contractility assessed by speckle tracking echocardiography (STE) after transjugular intrahepatic portosystemic shunt (TIPS) placement and its prognostic value in outcome. Methods: In this study, 206 (126 males) patients with liver cirrhosis receiving TIPS were included. In all study patients, conventional transthoracic echocardiography (TTE) was performed before and in the first weeks after TIPS placement to assess left and right ventricular volume, planar and functional parameters. Also, LV-GLS was measured by STE to assess left ventricular contractility as surrogate for myocardial dysfunction. Hemodynamic and clinical parameters were assessed before TIPS and during follow-up. Results: As expected, most conventional parameters of TTE showed a significant change after TIPS placement. However, neither the absolute values, nor the changes of conventional cardiac parameters of TTE before and after TIPS insertion were associated with survival. By contrast, an increase in contractility of more than 20% using STE after TIPS was an independent predictor of mortality. Conclusion: These results demonstrate that an increase of left ventricular contractility of more than 20% after TIPS insertion is an independent predictor of survival and this may identify patients at risk and in need of closer follow-up care.

Indexed as

cirrhosisdecompensationSTETIPS (transjugular intrahepatic portosystemic shunt)transthoracic echocardiography (TTE)

Identifiers

PMID41822086
PMCPMC12952439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.