Evidence map›Paper›PMID 41822049›Full record

ArticleNational science review2026

Ionic species programmable synaptic plasticity in multimodal nanofluidic devices.

Miliang Zhang, Ronghua Lan, Zhixiao Si, Jiqing Dai, Wenchao Liu, Wenbo Chang, Junjun Liu, Guoheng Xu, Kai Xiao

Abstract read
In one paragraph

Article in National science review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Miliang ZhangSchool of Materials and Environmental Engineering, Shenzhen Polytechnic University, Shenzhen 518055, China.
Ronghua LanSchool of Materials and Environmental Engineering, Shenzhen Polytechnic University, Shenzhen 518055, China.
Zhixiao SiDepartment of Biomedical Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Institute of Innovative Materials, Southern University of Science and Technology (SUSTech), Shenzhen 518055, China.
Jiqing DaiDepartment of Biomedical Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Institute of Innovative Materials, Southern University of Science and Technology (SUSTech), Shenzhen 518055, China.
Wenchao LiuDepartment of Biomedical Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Institute of Innovative Materials, Southern University of Science and Technology (SUSTech), Shenzhen 518055, China.
Wenbo ChangDepartment of Biomedical Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Institute of Innovative Materials, Southern University of Science and Technology (SUSTech), Shenzhen 518055, China.
Junjun LiuSchool of Materials and Environmental Engineering, Shenzhen Polytechnic University, Shenzhen 518055, China.
Guoheng XuDepartment of Biomedical Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Institute of Innovative Materials, Southern University of Science and Technology (SUSTech), Shenzhen 518055, China.
Kai XiaoDepartment of Biomedical Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Institute of Innovative Materials, Southern University of Science and Technology (SUSTech), Shenzhen 518055, China.ORCID https://orcid.org/0000-0001-9829-2707

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanofluidic devices have been widely utilized to simulate electronic functionalities recently, due to their unique ion transport behaviors, such as non-linear ion transport, selectivity etc. However, the correlation between the ion transport behavior and the transitions among various nanofluidic capacitive and inductive hysteresis still remains poorly understood, which impedes the development of nanofluidic systems. Here, we report a concentration-dependent transition between capacitive and inductive hysteresis in gold-nanoparticle-stacked nanochannels. Quantitative analysis reveals that this transition is governed by the interionic distance relative to the Bjerrum length, establishing a universal mechanism for ion transport modulation. Notably, our system enables unidirectional plasticity (both facilitation and depression) by simply altering the ionic species, demonstrating programmable plasticity without structural reconfiguration. Additionally, a high-pass filter (HPF) circuit with tunable cut-off frequency is implemented through two identical nanofluidic devices. These findings establish a new paradigm for multifunctional nanofluidic devices and provide a rational foundation for the design of aqueous-phase neuromorphic computing circuits.

Indexed as

artificial synapsenanofluidic capacitornanofluidic iontronicsnanofluidic memristorneuromorphic device

Identifiers

PMID41822049
PMCPMC12976602

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.