Evidence map›Paper›PMID 41821921›Full record

ArticleInfection and drug resistance2026

A Retrospective, Descriptive Analysis of MRSA Infections in a Low-Endemicity Region, Focusing on Empiric Treatment Adequacy.

Tiina Haapia, Jaana Vuopio, Rasmus Oksi, Tero Vahlberg, Jaakko Silvola, Mari Kanerva, MRSA Study Group, MRSA Study Group

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Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Tiina HaapiaInfection Control Unit, Turku University Hospital, The Wellbeing Services County of Southwest Finland, Turku, Finland.ORCID 0000-0002-0717-4578
Jaana VuopioInstitute of Biomedicine, University of Turku, Turku, Finland.
Rasmus OksiInfection Control Unit, Turku University Hospital, The Wellbeing Services County of Southwest Finland, Turku, Finland.
Tero VahlbergDepartment of Biostatistics, University of Turku and Turku University Hospital, Turku, Finland.
Jaakko SilvolaInstitute of Biomedicine, University of Turku, Turku, Finland.
Mari KanervaInfection Control Unit, Turku University Hospital, The Wellbeing Services County of Southwest Finland, Turku, Finland.
MRSA Study Group
MRSA Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previously, MRSA transmission and infections were mostly recognized as healthcare-associated. Community-associated MRSA (CA-MRSA) cases have become increasingly common, also in low-endemicity countries. Hence, also doctors in outpatient care encounter these patients. Despite increased general awareness on risk factors of MRSA carriage, it does not always influence clinical practice. As the total number of MRSA cases had increased in our region, it provoked us to analyze how this may have reflected the recognition of these infections and their empiric treatment adequacy in Hospital District of Southwest Finland (HDSWF). Methods: All new MRSA cases detected between 2007 and 2016 in Hospital District of Southwest Finland were retrospectively analyzed. This single-center study describes MRSA carriers, whose carriage was first detected from a clinical specimen. The cases were recognized from the hospital's MRSA registry, and their background data, including the antibiotic treatments given, were collected manually from electronic patient records. Results: A total of 280 MRSA cases having an active clinical infection were detected. Skin and soft tissue infections (SSTIs) were the most common infection type (76%; 213/280 cases). Information on antibiotic treatments were obtained in 46.8% (131/280) of the cases. In 81.7% (107/131) of the cases, the empiric treatment did not cover MRSA. After adjusting the treatment according to susceptibility results, MRSA was ultimately covered in 49.3% (68/138) of the cases. Conclusion: In low-endemicity settings, skin infections typically caused by

Indexed as

meticillin-resistant Staphylococcus aureusMRSAMRSA infectionMRSA treatment

Identifiers

PMID41821921
PMCPMC12978004

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.