Evidence map›Paper›PMID 41821785›Full record

ArticleFrontiers in gastroenterology (Lausanne, Switzerland)2023

Silvia Cruchet, Sandra Hirsch, Diana Villa-López, Mucio Moreno-Portillo, Juan C Palomo, Ana T Abreu-Abreu, Juan M Abdo-Francis, Carlos Jiménez-Gutiérrez, Martin Rojano, Gabriel López-Velázquez and 1 more

Abstract read
In one paragraph

Article in Frontiers in gastroenterology (Lausanne, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Silvia CruchetInstituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile, Santiago de Chile, Chile.
Sandra HirschInstituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile, Santiago de Chile, Chile.
Diana Villa-LópezGastroenterology Department, Hospital General Dr. Manuel Gea González, Mexico City, Mexico.
Mucio Moreno-PortilloGastroenterology Department, Hospital General Dr. Manuel Gea González, Mexico City, Mexico.
Juan C PalomoGastroenterology Department, Hospital General Dr. Manuel Gea González, Mexico City, Mexico.
Ana T Abreu-AbreuGastroenterology Department, Hospital Ángeles Pedregal, Mexico City, Mexico.
Juan M Abdo-FrancisGastroenterology Department, Hospital Ángeles Acoxpa, Mexico City, Mexico.
Carlos Jiménez-GutiérrezGastroenterology Department, Hospital General Dr. Manuel Gea González, Mexico City, Mexico.
Martin RojanoGastroenterology Department, Hospital General Dr. Manuel Gea González, Mexico City, Mexico.
Gabriel López-VelázquezLaboratorio de Biomoléculas y Salud Infantil, Instituto Nacional de Pediatría, Mexico City, Mexico.
Pedro Gutiérrez-CastrellónTraslational Research Division, International Scientific Council for Probiotics, Mexico City, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder in adults. Systematic reviews with meta-analyses have demonstrated the efficacy and safety of probiotics in improving symptoms of IBS. Aim: The aim of the study was to demonstrate the efficacy and safety of Methods: A randomized, double-blind, placebo-controlled clinical trial was conducted in 140 adults aged 18 years to 65 years with a diagnosis of IBS (based on the Rome IV criteria). After 2 weeks of washout, subjects were randomized to receive either 2 × 10 Results: In total, 70 subjects were allocated to receive Conclusions: A twice-a-day intervention for 14 weeks is safe and effective, reduces the symptoms associated with IBS in adults aged 18 years to 65 years, improves stool consistency, and reduces symptoms associated with anxiety after 6 weeks.

Indexed as

adultsirritable bowel syndromeL. reuteri ATCC PTA 6475L. reuteri DSM 17938randomized controlled (clinical) trial

Identifiers

PMID41821785
PMCPMC12952303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.