Evidence map›Paper›PMID 41821644›Full record

ArticleRespirology case reports2026

Long-Term Follow-Up of Pleuroparenchymal Fibroelastosis Associated With Crohn's Disease.

Yuhei Suzuki, Hiroaki Ikushima, Yutaro Ueki, Takashi Maeda, Keiichiro Hida, Keishi Yoshida, Chihiro Takeuchi, Hirokazu Urushiyama, Masanori Kawakami, Akihisa Mitani and 2 more

Abstract read
In one paragraph

Article in Respirology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuhei SuzukiDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Hiroaki IkushimaDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0002-7053-2841
Yutaro UekiDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Takashi MaedaDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Keiichiro HidaDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Keishi YoshidaDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0009-0008-2649-4105
Chihiro TakeuchiDepartment of Gastroenterology, Graduate School of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0002-2746-9189
Hirokazu UrushiyamaDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Masanori KawakamiDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0003-0207-7434
Akihisa MitaniDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0002-2669-2223
Mitsuhiro FujishiroDepartment of Gastroenterology, Graduate School of Medicine The University of Tokyo Tokyo Japan.
Hidenori KageDepartment of Respiratory Medicine, Graduate School of Medicine The University of Tokyo Tokyo Japan.ORCID https://orcid.org/0000-0003-3658-4442

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pleuroparenchymal fibroelastosis (PPFE) is a rare fibrosing interstitial lung disease that has been increasingly reported as a secondary condition following various underlying disorders including organ transplantation. However, reports on PPFE associated with inflammatory bowel disease (IBD), such as ulcerative colitis and Crohn's disease, remain extremely limited. We report the case of a 70-year-old man with Crohn's disease who developed slowly progressive upper-lobe-predominant lung lesions. Based on the clinical course, including the development of platythorax and pneumomediastinum, as well as the characteristic pulmonary function impairment and radiological findings, the patient was clinically diagnosed with PPFE. PPFE secondary to Crohn's disease is exceedingly rare, and this case is valuable in that longitudinal radiological progression could be followed in detail. This case highlights the importance of recognising PPFE as a pulmonary complication of Crohn's disease and underscores the value of careful longitudinal assessment using serial imaging and pulmonary function tests.

Indexed as

case reportCrohn's diseaseplatythoraxpneumomediastinumPPFE

Identifiers

PMID41821644
PMCPMC12978858

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.