Evidence map›Paper›PMID 41821631›Full record

ArticleFrontiers in neurology

NLR-FAR Index as a superior predictor of 30-day functional outcome after endovascular thrombectomy in acute ischemic stroke.

Xuchen Meng, Weijie Zhong, Dingzhong Tang, Zixian Mei, Tanjun Deng, Xin Lv, Jiexi Xiao, Yueqi Zhu, Yi Li

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PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xuchen Meng *Neurosurgery Department, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Weijie Zhong *Neurosurgery Department, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Dingzhong Tang *Neurology Department, Jinshan Branch of Shanghai Sixth People's Hospital, Shanghai, China.
Zixian MeiNeurosurgery Department, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tanjun DengNeurosurgery Department, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xin LvNeurosurgery Department, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jiexi XiaoNeurosurgery Department, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yueqi ZhuDepartment of Radiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi LiNeurosurgery Department, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To determine whether the neutrophil-to-lymphocyte ratio-fibrinogen-to-albumin ratio (NLR-FAR) Index predicts long-term prognosis in acute ischemic stroke patients undergoing endovascular thrombectomy (EVT). Introduction: Systemic inflammatory imbalance contributes to ischemic brain injury, but the combined effect of NLR and FAR on EVT outcomes has remained unclear. Methods: We retrospectively analyzed patients treated with EVT. A composite inflammatory-coagulation index, designated as the NLR-FAR Index, was defined as the product of NLR and FAR. The primary endpoint was 30-day functional outcome defined by the modified Rankin Scale (mRS), with poor outcome as mRS ≥3. Logistic regression and restricted cubic spline analyses were used to assess associations. Results: Of 254 patients, 121 (47.6%) had poor outcomes. Higher NLR, FAR, and especially NLR-FAR Index were significantly associated with poor prognosis. The NLR-FAR Index showed the strongest predictive effect (adjusted Conclusion: The NLR-FAR Index independently predicts functional outcomes after EVT and outperforms NLR or FAR alone. This accessible biomarker may aid early risk stratification and individualized management in acute ischemic stroke.

Indexed as

acute ischemic strokebiomarkerendovascular thrombectomyprognosis factorsSystemic inflammatory

Identifiers

PMID41821631
PMCPMC12975429

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.