Evidence map›Paper›PMID 41821581›Full record

Trial reportCancer communications (London, England)2026

Vebreltinib for Previously Treated Astrocytoma,

Zhaoshi Bao, Yake Xue, Yanhui Liu, Shouwei Li, Liang Wang, Yan Qu, Yonggao Mou, Rutong Yu, Jinsong Wu, Yu Yao and 23 more

Abstract readMulticenter StudyRandomized Controlled TrialClinical Trial, Phase III
In one paragraph

Trial report in Cancer communications (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Zhaoshi BaoBeijing Neurosurgical Institute, Beijing, P. R. China.
Yake XueDepartment of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, P. R. China.
Yanhui LiuDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, P. R. China.
Shouwei LiDepartment of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, P. R. China.
Liang WangDepartment of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shanxi, P. R. China.
Yan QuDepartment of Neurosurgery, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shanxi, P. R. China.
Yonggao MouDepartment of Neurosurgery/Neuro-oncology, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, P. R. China.
Rutong YuDepartment of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, P. R. China.
Jinsong WuDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, P. R. China.
Yu YaoDepartment of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, P. R. China.
Kai ShuDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, P. R. China.
Guangyuan HuDepartment of Neurosurgery, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, Hubei, P. R. China.
Linbo CaiDepartment of Neurosurgery, Guangdong Sanjiu Brain Hospital, Guangzhou, Guangdong, P. R. China.
Wenbin LiDepartment of Neuro-oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing, P. R. China.
Xiaoguang QiuDepartment of Radiation Oncology, Beijing Tiantan Hospital, Capital Medical University, Beijing, P. R. China.
Yunqian LiDepartment of Neurosurgery, The First Hospital of Jilin University, Changchun, Jilin, P. R. China.
Lei ZhangDepartment of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, P. R. China.
Songtao QiDepartment of Neurosurgery, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, P. R. China.
Ying JiDepartment of Neurosurgery, The First Affiliated Hospital of University of Science and Technology of China, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, P. R. China.
Chunxiao MaDepartment of Neurosurgery, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, Henan, P. R. China.
Wenbin MaDepartment of Neurosurgery, Peking Union Medical College Hospital, Beijing, P. R. China.
Gang LiDepartment of Neurosurgery, Qilu Hospital of Shandong University, Jinan, Shandong, P. R. China.
Rongjie TaoDepartment of Neurosurgery, Shandong Tumor Hospital, Jinan, Shandong, P. R. China.
Chongran SunDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, P. R. China.
Ligang ChenDepartment of Neurosurgery, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, P. R. China.
Sheng-Qing LvDepartment of Neurosurgery, Xinqiao Hospital, Third Military Medical University (Army Medical University), Chongqing, P. R. China.
Peng LiangDepartment of Neurosurgery, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang, P. R. China.
Hao PanDepartment of Neurosurgery, General Hospital of Eastern Theater Command of Chinese People's Liberation Army, Nanjing, Jiangsu, P. R. China.
Woo Yat Ming PeterThe Otto Wong Brain Tumour Centre, Division of Neurosurgery, Department of Surgery, The Chinese University of Hong Kong, New Territories, Hong Kong, P. R. China.
Chan Tat Ming DannyThe Otto Wong Brain Tumour Centre, Division of Neurosurgery, Department of Surgery, The Chinese University of Hong Kong, New Territories, Hong Kong, P. R. China.
Qing MaoDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, P. R. China.
Xinting WeiDepartment of Neurosurgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, P. R. China.
Tao JiangBeijing Neurosurgical Institute, Beijing, P. R. China.ORCID https://orcid.org/0000-0002-7008-6351

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AstrocytomaBrain NeoplasmsGlioblastomaAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBenzimidazolesFemaleHumansIsocitrate DehydrogenaseMaleMiddle AgedMutationOncogene Proteins, FusionQuinolonesTemozolomide4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-oneBenzimidazolesIsocitrate DehydrogenaseOncogene Proteins, FusionQuinolonesTemozolomide

Identifiers

PMID41821581
PMCPMC12976379

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.