Evidence map›Paper›PMID 41821483›Full record

ArticleJournal of the American Chemical Society2026

Boron-Mediated Hydroalkylation of Unactivated Olefins: An

Hanwen Zhang, Ruocheng Sang, Gianluca Simionato, Jasper L Tyler, Adam Noble, Varinder K Aggarwal

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hanwen ZhangSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.
Ruocheng SangSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.ORCID 0000-0003-2512-9479
Gianluca SimionatoSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.
Jasper L TylerSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.ORCID 0000-0002-3155-1847
Adam NobleSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.ORCID 0000-0001-9203-7828
Varinder K AggarwalSchool of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, U.K.ORCID 0000-0003-0344-6430

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transition metal-catalyzed hydroalkylations offer efficient routes to install alkyl fragments onto readily available olefins. However, the formation of quaternary carbon centers through olefin hydroalkylations with tertiary alkyl electrophiles remains a formidable synthetic challenge. Difficulty arises as a result of steric congestion, which slows the rate of oxidative addition and promotes deleterious β-hydride elimination. Here, we report a boron-mediated coupling strategy using nickel/photoredox dual catalysis that circumvents these limitations and enables

Identifiers

PMID41821483
PMCPMC13022885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.