Evidence map›Paper›PMID 41821419›Full record

ArticleJournal of cardiovascular electrophysiology2026

Sustained Idiopathic Outflow Tract Ventricular Tachycardia: Clinical Evidence for RVOT Predominance.

Moneeb Khalaph, Nadica Trajkovska, Maxim Didenko, Mustapha El Hamriti, Guram Imnadze, Denise Guckel, Philipp Lucas, Martin Braun, Thomas Fink, Vanessa Sciacca and 7 more

Abstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Moneeb KhalaphDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.ORCID 0009-0004-2454-1335
Nadica TrajkovskaDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Maxim DidenkoDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Mustapha El HamritiClinic for Cardiology/Electrophysiology, GZO-Spital Wetzikon, Zürich, Switzerland.
Guram ImnadzeClinic for Electrophysiology, University Hospital Ruppin-Brandenburg, Germany.
Denise GuckelDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Philipp LucasDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Martin BraunDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Thomas FinkDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Vanessa SciaccaDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Ersan AkkayaDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Sebastian E BeyerTelemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Massachusetts General Hospital, Boston, Massachusetts, USA.
Hassan El-ShirbinyDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Maximilian MörsdorfDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Christian SohnsDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.ORCID 0000-0003-0490-5862
Philipp SommerDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.
Angeliki DarmaDepartment of Electrophysiology, Heart and Diabetes Center NRW, Ruhr University Bochum, Bad Oeynhausen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIdiopathic outflow tract premature ventricular contractions (PVCs) are most commonly localized in the right ventricular outflow tract (RVOT). The clinical significance of sustained outflow tract ventricular tachycardia (OT-VT) regarding any predominance to one specific anatomic area remains uncertain. SUBJECTIVE: This study aimed to characterize the clinical and procedural features of patients with idiopathic sustained OT-VT and determine whether the site of origin can be predicted from clinical presentation.

methodsThis retrospective cohort included 35 consecutive patients with documented sustained OT-VT (≥ 30 s), from over 400 patients referred for idiopathic outflow tract arrhythmia ablation. Baseline clinical and echocardiographic characteristics were collected and procedural data reviewed. Sites of arrhythmia origin were identified by electroanatomic mapping and ablation outcomes.

resultsSustained OT-VT arose exclusively from right-sided outflow tract foci, most commonly the postero- or anteroseptal RVOT (n = 26, 74.3% and n = 6, 17.1%, respectively) and less frequently from the posterolateral (n = 3, 8.6%). No cases of sustained VT from the LVOT were observed. Acute ablation success was achieved in all patients. During 12 months of follow-up, recurrence occurred in three patients (8.6%), all of whom were successfully managed with repeat ablation. No complications were observed.

conclusionIn patients with structurally normal hearts, sustained OT-VT in our cohort arose exclusively from the RVOT. Recognition of this pattern can guide mapping and ablation strategies.

Indexed as

Tachycardia, VentricularVentricular Premature ComplexesAction PotentialsAdultAgedCatheter AblationElectrophysiologic Techniques, CardiacFemaleHeart RateHumansMaleMiddle AgedRecurrenceRetrospective StudiesTime FactorsTreatment Outcomecatheter ablationLVOTOT‐VToutflow tract arrhythmiapremature ventricular contraction (PVC)RVOTventricular tachycardia

Identifiers

PMID41821419
PMCPMC13182212

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.