Evidence map›Paper›PMID 41821246›Full record

ArticleHealth expectations : an international journal of public participation in health care and health policy2026

The Development and Acceptability of a Psychology-Based Intervention for Debilitating Symptom Complexes Attributed to Ticks.

Anita L Dharan, Valerie M Z Yap, Richard A Kanaan, Georgina Oliver, Yen D Y Sim, Sabine Braat, Georgia Cotter, Mary Lou Chatterton, Cathrine Mihalopoulos, Sarah J Wilson and 1 more

Abstract read
In one paragraph

Article in Health expectations : an international journal of public participation in health care and health policy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The Development and Acceptability of a Psychology-Based Intervention for Debilitating Symptom Complexes Attributed to Ticks.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anita L DharanDepartment of Psychiatry, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.ORCID 0000-0002-3968-656X
Valerie M Z YapDepartment of Psychiatry, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.
Richard A KanaanDepartment of Psychiatry, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.
Georgina OliverDepartment of Psychiatry, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.ORCID 0000-0002-9215-2225
Yen D Y SimDepartment of Psychiatry, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.
Sabine BraatCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Victoria, Australia.
Georgia CotterDepartment of Psychiatry, University of Melbourne, Austin Health, Heidelberg, Victoria, Australia.
Mary Lou ChattertonMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Victoria, Australia.
Cathrine MihalopoulosMonash University Health Economics Group, School of Public Health and Preventive Medicine, Monash University, Victoria, Australia.
Sarah J WilsonMelbourne School of Psychological Sciences, The University of Melbourne, Victoria, Australia.
Trudie ChalderDepartment of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

Funding

National Health and Medical Research Council AP1169827National Institute for Health Research Maudsley Biomedical Research Centre
6 · The paper itself

Abstract

backgroundDebilitating Symptom Complexes Attributed to Ticks (DSCATT) is a chronic, debilitating illness associated with tick bites in Australia. DSCATT is of unknown aetiology, can impact emotional well-being and has no recognised treatments.

objectiveThe development and piloting of a novel psychotherapeutic adjunctive intervention for DSCATT that aimed to increase daily functioning, improve quality of life and reduce the impact of symptoms in people with DSCATT.

methodsThis is a single-site, intervention development and acceptability study. The intervention was developed iteratively according to a Human-Centred Design (HCD) approach and manualised across four phases, with input from end users at each phase: qualitative interviews, development of the intervention, piloting, and revising and refining the intervention. Acceptability of the prototype intervention was evaluated through thematic template analysis of exit interviews. Self-report measures were completed before and after intervention delivery.

resultsFollowing qualitative interviews with 13 participants (11 females and 2 males; aged 35-70 years), the intervention was informed by an Acceptance and Commitment Therapy (ACT) model interwoven with cognitive and behavioural strategies that targeted DSCATT-specific difficulties. The manualised intervention consisted of 12 1-h weekly individual sessions, delivered by psychologists via Telehealth (video call or telephone). Modules addressed the six core psychological processes of ACT, alongside DSCATT-specific modules addressing cognitive function, sleep and social relationships. Pilot testing and follow-up interviews were conducted in a separate sample of six individuals with DSCATT (all females; aged 46-71 years). All participants reported that the approach benefited their emotional well-being and overall health and would recommend it to others with DSCATT.

conclusionsThis is a novel and theoretically driven psychotherapeutic intervention for DSCATT, co-produced with patient involvement across four phases. Pilot testing suggested the manualised intervention was feasible and acceptable, supporting future evaluation of feasibility and treatment outcomes with randomised controlled trials. PATIENT OR PUBLIC CONTRIBUTION: This study involved the engagement and participation of individuals with DSCATT across four stages of the project, according to an HCD approach-the choice of the intervention; the development of the intervention; the piloting of the intervention, and the assessment of the intervention.

trial registrationThe pilot study component of this project was prospectively registered on the Australian and New Zealand Clinical Trial Registry (ANZCTR); trial ID: ACTRN12621001032842.

Indexed as

Acceptance and Commitment TherapyPatient Acceptance of Health CareTick BitesAdultAgedAnimalsAustraliaFemaleHumansInterviews as TopicMaleMiddle AgedPilot ProjectsPsychological Well-BeingQualitative ResearchQuality of Life

Identifiers

PMID41821246
PMCPMC13080887

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.