Evidence map›Paper›PMID 41821038›Full record

Trial reportAddiction science & clinical practice2026

Trial experiences with dyadic breathalyzer technology for alcohol monitoring and feedback among couples living with HIV in South Africa.

Amy A Conroy, Rita M Butterfield, Buyisile Chibi, Lindani Msimango, Tyrel J Starks

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Addiction science & clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05756790 (Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05756790 nacompletednot on this map

Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa

TypeinterventionalSponsorUniversity of California, San FranciscoRan2023 to 2024Enrolled186ConditionsHIV/AIDS, Alcohol AbuseArmsMotivational Interviewing, Motivational Interviewing plus Breathalyzer
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amy A ConroyDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA. amy.conroy@ucsf.edu.
Rita M ButterfieldDepartment of Medicine, University of California San Francisco, San Francisco, CA, USA.
Buyisile ChibiHuman Sciences Research Council, Centre for Community Based Research, Sweetwaters, KwaZulu-Natal, South Africa.
Lindani MsimangoHuman Sciences Research Council, Centre for Community Based Research, Sweetwaters, KwaZulu-Natal, South Africa.
Tyrel J StarksDepartment of Psychology, Hunter College of the City University of New York (CUNY), New York, NY, USA.

Funding

Couple-Based Motivational Interviewing with Technology to Reduce Alcohol Consumption in HIV+ South African Couples - Administrative SupplementR34AA029649 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CONROY, AMY ANNE · 2021 to 2023
$778k
NIAAA NIH HHS P60-AA032189NIAAA NIH HHS R34 AA029649NIAAA NIH HHS R34-AA029649
6 · The paper itself

Abstract

backgroundDyadic monitoring tools could enhance partner awareness of drinking behaviors and prompt timely communication and supportive responses during alcohol use. We posited that real-time blood alcohol content (BAC) levels combined with motivational interviewing (MI) could facilitate couple communication, communal coping, and support, enabling couples to set joint goals and reduce alcohol consumption. We qualitatively explored the positive and negative experiences of trial participants who received mobile breathalyzer technology with couples MI to reduce unhealthy alcohol use in South Africa.

methodsThirty couples (60 individuals) participated in a pilot trial combining couples-based MI with mobile breathalyzers. Index participants reporting unhealthy alcohol use and on antiretroviral therapy were assigned a portable breathalyzer linked to a smartphone app to complete twice-daily BAC tests. Partners received real-time SMS notifications of these BAC results. Both partners engaged in three MI sessions to reflect on drinking patterns and set alcohol reduction goals together. Transcripts from audio-recorded sessions and exit interviews from a subset of 12 individuals were analyzed using framework analysis. The data were coded for positive and negative experiences of using the breathalyzers and dyadic mechanisms of behavior change.

resultsParticipants averaged 35.9 years old and had relationships averaging 6.6 years. Most couples (66.7%) had two partners reporting unhealthy drinking. Couples found the mobile breathalyzer technology engaging and enjoyable due to its novelty and social curiosity it sparked. Despite challenges related to connectivity issues, privacy, and technical difficulties, participants generally found workarounds and leveraged study resources like power banks and dedicated navigators. Participants described how the breathalyzers enhanced self-awareness of alcohol consumption, promoted home-based drinking, and fostered partner support and communication, though it sometimes led to tensions over technology allocation and usage, when only one partner received the device.

conclusionsCouples in a low-resource setting in South Africa successfully used breathalyzers to self-monitor alcohol consumption. Breathalyzers could be used to increase personal motivation to reduce alcohol use, activate partner support, and help partners coordinate efforts to achieve drinking goals. Addressing structural challenges like cellular connectivity, as well as dyadic equity by providing both partners with breathalyzers, will be critical to maximizing breathalyzer uptake and intervention impact in resource-poor settings.

trial registrationNCT05756790; registration date: 3/6/2023.

Indexed as

Alcohol DrinkingHIV InfectionsMotivational InterviewingAdultBlood Alcohol ContentBreath TestsFemaleHumansMaleMiddle AgedMobile ApplicationsPilot ProjectsSmartphoneSouth AfricaBlood Alcohol ContentAlcohol useAntiretroviral therapyCouplesHIV/AIDSSouth Africa

Identifiers

PMID41821038
PMCPMC13020353

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.