Evidence map›Paper›PMID 41821005›Full record

ArticleActa neuropathologica communications2026

Low-grade peripheral inflammation accelerates retinal amyloid pathology and dysfunction in an Alzheimer's disease mouse model.

Lien Cools, Yasmin Dahdouh-Guebas, Iene Kemps, Steven Bergmans, Jonas Castelein, Roosmarijn E Vandenbroucke, Lien Van Hoecke, Lies De Groef

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lien Cools *Cellular Communication and Neurodegeneration Research Group, Animal Physiology and Neurobiology Division, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Yasmin Dahdouh-Guebas *Cellular Communication and Neurodegeneration Research Group, Animal Physiology and Neurobiology Division, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Iene KempsCellular Communication and Neurodegeneration Research Group, Animal Physiology and Neurobiology Division, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Steven BergmansCellular Communication and Neurodegeneration Research Group, Animal Physiology and Neurobiology Division, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium.
Jonas CasteleinVIB-UGent Center for Inflammation Research, VIB, Ghent, Belgium.
Roosmarijn E VandenbrouckeVIB-UGent Center for Inflammation Research, VIB, Ghent, Belgium.
Lien Van Hoecke *VIB-UGent Center for Inflammation Research, VIB, Ghent, Belgium.
Lies De Groef *Cellular Communication and Neurodegeneration Research Group, Animal Physiology and Neurobiology Division, Department of Biology, Leuven Brain Institute, KU Leuven, Leuven, Belgium. lies.degroef@kuleuven.be.

Funding

Fonds Wetenschappelijk Onderzoek 11M3324NFonds Wetenschappelijk Onderzoek 1268823NFonds Wetenschappelijk Onderzoek 1SHC824NStichting Alzheimer Onderzoek 2020/0032Stichting Alzheimer Onderzoek 2021/0036
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseaseElectroretinogramLow-grade peripheral inflammationRetinaRetinal imaging

Identifiers

PMID41821005
PMCPMC13371543

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.