Evidence map›Paper›PMID 41820934›Full record

SynthesisBMC oral health2026

Extraction of first primary molars and significance of space loss: a systematic review and meta-analysis.

Ahmed Kamal El-Motayam, Mostafa A Hassan, Mais Medhat Sadek, Rim Fathalla, Nour Wahba, Reem Mahmoud, Shereen Hassan Elshamy

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmed Kamal El-MotayamDepartment of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University, 11 Al Saraya street, Manial, Cairo, Egypt. ahmed.elmotayam@dentistry.cu.edu.eg.
Mostafa A HassanRoyal Dentists Institute, 74 Mohamed Farid Street, Cairo, Nasr City, Egypt.
Mais Medhat SadekUniversity of Sharjah,Ain Shams University, P. O. Box 82828, Cairo, Egypt.
Rim FathallaFaculty of Dentistry, Suez Canal University, 4.5 km ring road, Ismailia, Egypt.
Nour WahbaFaculty of Dentistry, Ain Shams University, El-Khalifa El-Mamoun Street, Cairo, Egypt.
Reem MahmoudFaculty of Dentistry, British University in Egypt, Suez Desert Road, P.O. Box 43, Cairo, El Sherouk City, 11837, Egypt.
Shereen Hassan ElshamyDepartment of Pediatric Dentistry and Dental Public Health, Faculty of Dentistry, Cairo University, 11 Al Saraya street, Manial, Cairo, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo quantify space loss following premature extraction of primary first molars (Ds) over a follow-up period of at least six months and evaluate its clinical implications. MATERIALS AND

methodsA systematic search of PubMed, Cochrane Library, LILACS, Web of Science, and Embase was conducted. Only longitudinal split-mouth cohort studies were included. The primary outcome was the amount of space loss in the extraction region, measured against the contralateral control side.

results7 studies were included, comprising 141 children for maxillary analysis and 171 children for mandibular analysis. Meta-analysis for space loss revealed a mean difference (MD) of -0.52 mm (95% CI: -0.79 to -0.26; p < 0.001) in the maxilla after 9–12 months, and − 1.78 mm (95% CI: -2.09 to -1.47; p < 0.001) in the mandible after 8–9 months.

conclusionsPremature loss of Ds in children aged 6–9 years results in space loss of -0.52 mm in the maxilla and − 1.78 mm in the mandible. Space maintainers are indicated following mandibular extractions, while maxillary cases may not require routine intervention.

Indexed as

MolarTooth, DeciduousTooth ExtractionChildHumansMandibleMaxillaSpace Maintenance, OrthodonticPremature tooth lossPrimary first molarSpace lossSpace maintainerSpatial changes

Identifiers

PMID41820934
PMCPMC13063717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.