Evidence map›Paper›PMID 41820799›Full record

ArticlePlant, cell & environment2026

An Engineered Abscisic Acid Receptor Enhances ABA Signaling and Improves Abiotic Stress Tolerance in Rice.

Jaeeun Song, In-Sik Song, Rigyeong Kim, Sangkyu Park, Eun-Hye Kim, Hyo Lee, Saet Buyl Lee, Hyunwoo Cho, Sangho Lee, Ok Ran Lee and 1 more

Abstract read
In one paragraph

Article in Plant, cell & environment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jaeeun SongPlant Biomaterials and Biotechnology Division, National Institute of Agricultural Sciences, Rural Development Administration, JeonJu, South Korea.ORCID https://orcid.org/0000-0003-4893-9140
In-Sik SongPlant Biomaterials and Biotechnology Division, National Institute of Agricultural Sciences, Rural Development Administration, JeonJu, South Korea.
Rigyeong KimPlant Biomaterials and Biotechnology Division, National Institute of Agricultural Sciences, Rural Development Administration, JeonJu, South Korea.
Sangkyu ParkPlant Biomaterials and Biotechnology Division, National Institute of Agricultural Sciences, Rural Development Administration, JeonJu, South Korea.
Eun-Hye KimPlant Biomaterials and Biotechnology Division, National Institute of Agricultural Sciences, Rural Development Administration, JeonJu, South Korea.
Hyo LeePlant Biomaterials and Biotechnology Division, National Institute of Agricultural Sciences, Rural Development Administration, JeonJu, South Korea.
Saet Buyl LeePlant Biomaterials and Biotechnology Division, National Institute of Agricultural Sciences, Rural Development Administration, JeonJu, South Korea.ORCID https://orcid.org/0000-0002-5549-0081
Hyunwoo ChoDepartment of Biological Sciences, Sungkyunkwan University, Suwon, South Korea.
Sangho LeeDepartment of Biological Sciences, Sungkyunkwan University, Suwon, South Korea.ORCID https://orcid.org/0000-0003-3886-4579
Ok Ran LeeDepartment of Applied Plant Science, College of Agriculture and Life Sciences, Chonnam National University, Gwangju, South Korea.ORCID https://orcid.org/0000-0002-6928-5863
Beom-Gi KimPlant Biomaterials and Biotechnology Division, National Institute of Agricultural Sciences, Rural Development Administration, JeonJu, South Korea.ORCID https://orcid.org/0000-0002-4887-1775

Funding

NRF RS-2025-00513994NRF RS-2025-16069622Rural Development Administration PJ017209
6 · The paper itself

Abstract

Abscisic acid (ABA) is a key phytohormone that orchestrates adaptive responses in plants exposed to abiotic stress. The ABA signaling cascade is triggered by ABA-mediated binding of PYRABACTIN RESISTANCE1-LIKE (PYL) receptors to clade A Type 2 C protein phosphatases (PP2CAs). In Arabidopsis thaliana, several constitutively active variants of ABA receptors have been described, offering valuable tools for improving plant tolerance to environmental stresses. To identify amino acid residues in the rice ABA receptor OsPYL5 that are involved in ABA-independent interactions, we implemented a random mutagenesis strategy followed by yeast two-hybrid (Y2H) screening. We identified residues L-93 and N-102 as key residues that influence the ABA independent interaction of OsPYL5 with OsPP2CA51. Substituting these residues with T or Y significantly enhanced the activity of an ABA-responsive reporter in rice protoplasts, even in the absence of ABA treatment. We therefore engineered a double-point mutant, OsPYL5

Indexed as

Abscisic AcidOryzaPlant ProteinsReceptors, Cell SurfaceSignal TransductionStress, PhysiologicalDrought ResistanceGene Expression Regulation, PlantGerminationPlant Growth RegulatorsPlants, Genetically ModifiedAbscisic AcidPlant Growth RegulatorsPlant ProteinsReceptors, Cell SurfaceABAabiotic stress toleranceOryza sativaOsPYL5random mutagenesis

Identifiers

PMID41820799
PMCPMC13353701

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.