Evidence map›Paper›PMID 41820769›Full record

ArticleNeurocritical care2026

Should We Do an Individual Management of Septic Shock in Neurocritically Ill Patients? A Proposal of a Conceptual Algorithm.

Marcos Rolando, Francisco Zarra, Walter Videtta

Abstract readEditorial
PubMed Publisher
In one paragraph

Article in Neurocritical care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marcos Rolando *Department of Intensive Care, Hospital Central de San Isidro, Av. Santa Fe 431, B1641, Acassuso, Buenos Aires, Argentina.ORCID http://orcid.org/0009-0003-8148-8422
Francisco Zarra *Department of Intensive Care, University of Buenos Aires School of Medicine, Hospital Eva Perón de Merlo, Buenos Aires, Argentina. franciscozarra@hotmail.com.ORCID http://orcid.org/0009-0002-9565-6944
Walter VidettaDepartment of Intensive Care, University of Buenos Aires School of Medicine, Hospital Eva Perón de Merlo, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-0543-0769

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Septic shock (SS) constitutes a complex and potentially severe entity associated with a high mortality rate worldwide.The neurocritically ill patient represents a vulnerable population with a marked tendency to develop SS . In turn, invasive neuromonitoring devices-such as external ventricular drainage (EVD)-may predispose to intracranial infections, which in some cases may progress to SS . Early goal-directed therapy (EGDT) was initially proposed by Rivers et al. for the management of SS. However, lately its application has been discussed due to its higher hospitalization costs and excessive heterogeneity among patients in the baseline inflammation levels and stage of organ dysfunction . Thus, the strategy for addressing these scenarios more effectively might be an individualized approach. To solve this research question, we proposed a novel conceptual algorithm to approach neurocritically ill patients with SS to improve the DO

Indexed as

AlgorithmsArterial PressureCerebrovascular CirculationCritical CareCritical IllnessShock, SepticHumansCPPEGDTMAPResuscitationSeptic shock

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.