ArticleInternational microbiology : the official journal of the Spanish Society for Microbiology2026
Genomic, metabolomic, and functional properties of probiotic lactic acid bacteria isolated from Indonesian stingless bee honey.
Article in International microbiology : the official journal of the Spanish Society for Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
Abstract
Stingless bee honey (SBH) is recognized as a functional food with antibacterial, antioxidant, and anticancer properties. This study aimed to isolate and characterize lactic acid bacteria (LAB) with potential probiotic, antibacterial, and antioxidant activities from SBH. LAB were isolated from honey samples of seven Indonesian stingless bee species and screened for antibacterial activity. Five isolates with the highest antibacterial activity were selected for further characterization, including whole genome sequencing (WGS), probiotic property assessment, antioxidant activity, α-amylase inhibitory potential of their cell-free supernatants (CFS), and metabolomic profiling. The isolates were identified as Lacticaseibacillus rhamnosus (TB-3, HI-1, and TS-4) and Pediococcus acidilactici (HI-5 and LT-3) based on WGS analysis. Genome-mining revealed biosynthetic gene clusters (BGCs), including T3PKS, RiPP-like and bacteriocin. All isolates exhibited good probiotic properties with high survival rates under simulated gastrointestinal conditions. CFS of the isolates exhibited strong antibacterial activity against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa, as well as significant antioxidant capacity (DPPH, ABTS, and FRAP), high polyphenol and flavonoid contents, and α-amylase inhibition. Untargeted metabolomic analysis using UHPLC-HRMS revealed distinct metabolite profiles with several potential bioactive compounds. This study highlights the potential of SBH-derived LAB as probiotic candidates with antibacterial and antioxidant properties. The integration of genomic and metabolomic approaches offers valuable insights into their application in functional foods and nutraceuticals.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.