ArticleEuropean radiology2026
Preoperative skeletal muscle assessment as a predictor of liver regeneration in living donor liver transplantation.
Article in European radiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study investigated whether liver regeneration after living donor liver transplantation (LDLT) is associated with baseline skeletal muscle status, based on preoperative computed tomography (CT). MATERIALS AND
methodsIn this retrospective cohort study, skeletal muscle mass and skeletal muscle attenuation (SMA) from preoperative CT scans of living liver donors who underwent right hemihepatectomy were analyzed. The liver regeneration rate was calculated as the percentage of remnant liver volume on postoperative CT performed 45-90 days after surgery, divided by the estimated preoperative left hemiliver volume. Logistic regression analysis identified risk factors for suboptimal regeneration, defined as the lower 10
resultsA total of 171 living liver donors (101 men, 70 women; median age, 34 years) were included. Lower SMA, measured on contrast-enhanced CT images acquired in the portal venous phase, was significantly and independently associated with an increased risk of suboptimal regeneration (adjusted odds ratio: 1.14 per 1 Hounsfield unit decrease; 95% confidence interval: 1.04-1.25). SMA showed a significant positive correlation with liver regeneration rate (ρ = 0.191, p = 0.013).
conclusionsLower SMA, as assessed on preoperative CT, is associated with suboptimal liver regeneration following right hemihepatectomy for living donor liver transplantation. KEY POINTS: Question Adequate liver regeneration is crucial after living donor liver transplantation, but reliable donor-related prognostic factors to predict it remain limited. Findings Lower skeletal muscle attenuation on portal venous phase CT acquired 45-90 days after right hemihepatectomy was independently associated with suboptimal liver regeneration among living liver donors. Clinical relevance Preoperative skeletal muscle attenuation may help identify living liver donors at risk for suboptimal liver regeneration, offering a potential tool for donor selection and personalized assessment to ensure adequate postoperative liver volume and long-term hepatic reserve in clinical practice.
Indexed as
Identifiers
41820585What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.