Effects of individualized PEEP titration on intraoperative cardiac output in thoracoscopic lung surgery: a prospective randomized trial.

Mengyue Zhu, Tianhao Song, Qinyu Bao, Jing Wang, Jin Wang, Weiyi Wang, Zhenghuan Song, Jing Tan

Abstract readRandomized Controlled Trial

In one paragraph

Trial report in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mengyue Zhu *Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.

Tianhao Song *Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.

Qinyu BaoJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.

Jing WangJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.

Jin WangJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China.

Weiyi WangDepartment of Anesthesiology, Jiangsu Cancer Hospital, Nanjing, China.

Zhenghuan SongJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China. songzhenghuan@njmu.edu.cn.

Jing TanJiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China. tanjing@njmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Personalized positive end-expiratory pressure (PEEP) based on pulmonary compliance may improve intraoperative hemodynamics and postoperative outcomes in thoracic surgery. This study aimed to evaluate the effect of individualized, compliance-guided PEEP titration on cardiac output (CO) and postoperative pulmonary complications (PPCs) in patients undergoing video-assisted thoracoscopic pulmonary resection. In this prospective randomized controlled trial, 80 patients scheduled for thoracoscopic pulmonary resection were allocated to either an individualized PEEP group (Group N) or a fixed PEEP group (Group C). Group N received dynamic PEEP titration starting at 15 cmH

Indexed as

Cardiac OutputLungPositive-Pressure RespirationThoracic Surgery, Video-AssistedAgedFemaleHemodynamicsHumansMaleMiddle AgedPostoperative ComplicationsProspective StudiesThoracoscopyCardiac outputHemodynamic parametersIndividualized PEEPOne-lung ventilationThoracoscopic pulmonary resection

Identifiers

PMID41820516

DOI10.1038/s41598-026-43122-6

PMCPMC13102971

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.