Evidence map›Paper›PMID 41820376›Full record

ArticleNPJ Parkinson's disease2026

PARK19 truncation mutant Dnajc6 causes lysosomal deficiency-induced upregulation of pathologic α-synuclein and neurodegeneration of substantia nigra dopaminergic cells in PARK19 knockin mice.

Hung-Li Wang, Ying-Ling Chen, Tai-Ju Chiu, Ching-Chi Chiu, Yi-Hsin Weng, Shu-Yu Liu, Allen Hon-Lun Li, Tu-Hsueh Yeh

Abstract read
In one paragraph

Article in NPJ Parkinson's disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hung-Li Wang *Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Ying-Ling Chen *Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan.
Tai-Ju ChiuGraduate Institute of Biomedical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Ching-Chi ChiuHealthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Yi-Hsin WengDivision of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Shu-Yu LiuDepartment of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.
Allen Hon-Lun LiDepartment of Anesthesiology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.
Tu-Hsueh YehDepartment of Neurology, Taipei Medical University Hospital, Taipei, Taiwan. do2739@tmu.edu.tw.

Funding

Chang Gung Medical Foundation CMRPD1M0142National Science and Technology Council, Taiwan NSTC 113- 2320-B-182-026-MY3National Science and Technology Council, Taiwan NSTC 114-2314-B-038-061
6 · The paper itself

Abstract

Homozygous (Q789X) DNAJC6 mutation causes PARK19. Q787 of Dnajc6 corresponds to Q789 of DNAJC6. Dnajc6

Identifiers

PMID41820376
PMCPMC13121519

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.