Evidence map›Paper›PMID 41819828›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2026

Assessment of CCR2 PET as a Biomarker for Head and Neck Squamous Cell Carcinoma.

Alexandria Li, Deborah Sultan, Gyu Seong Heo, Lisa Detering, Divangana Lahad, Hannah Luehmann, Xiaohui Zhang, Rajiu Venkatesan, Jennifer Frye, Julie Belmar and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Alexandria LiMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Deborah SultanMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Gyu Seong HeoMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Lisa DeteringMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Divangana LahadMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Hannah LuehmannMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Xiaohui ZhangMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Rajiu VenkatesanMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Jennifer FryeMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Julie BelmarDepartment of Medicine, Washington University in St. Louis, St Louis, Missouri.
Salma RamadanDepartment of Otolaryngology, Washington University in St. Louis, St. Louis, Missouri.
Robert CrowderDepartment of Otolaryngology, Washington University in St. Louis, St. Louis, Missouri.
Ying-Hwey NaiMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Joan TaoDepartment of Medicine, University of Missouri, Columbia; Missouri.
Robert GroplerMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Richard LaforestMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Ryan S JacksonDepartment of Otolaryngology, Washington University in St. Louis, St. Louis, Missouri.
Rebecca ChernockDepartment of Otolaryngology, Washington University in St. Louis, St. Louis, Missouri.
Chieh-Yu LinSiteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri.
Shunqiang LiSiteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri.
Sidharth PuramDepartment of Otolaryngology, Washington University in St. Louis, St. Louis, Missouri.
Farrokh DehdashtiMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri.
Yongjian LiuMallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, Missouri; yongjianliu@wustl.edu.

Funding

Training/DisseminationP41EB025815 · NIBIB · WASHINGTON UNIVERSITY · PI Robert J. Gropler · 2018 to 2026
$12.7M
Acquisition of high-resolution PET/CT preclinical imaging instrument at MIRS10OD030403 · OD · WASHINGTON UNIVERSITY · PI SHOGHI, KOORESH ISAAC · 2021 to 2021
$929k
NIBIB NIH HHS P41 EB025815NIH HHS S10 OD030403
6 · The paper itself

Abstract

Because of the lack of prognostic biomarkers, most patients with head and neck squamous cell carcinoma (HNSCC) are diagnosed at an advanced stage of the disease, leading to poor overall survival. There is an unmet need to identify biomarkers for the assessment of HNSCC. The goal of this study was to assess C-C chemokine receptor type 2 (CCR2) as a new diagnostic biomarker for HNSCC.

Indexed as

Biomarkers, TumorHead and Neck NeoplasmsPositron-Emission TomographyReceptors, CCR2Squamous Cell Carcinoma of Head and NeckAnimalsCell Line, TumorCopper RadioisotopesFemaleGermaniumHumansMiceOrganometallic CompoundsPropionatesBiomarkers, TumorCCR2 protein, humanCopper RadioisotopesGermaniumOrganometallic CompoundspropagermaniumPropionatesReceptors, CCR2biomarkerCCR2HNSCCmacrophagepropagermaniumtumor

Identifiers

PMID41819828
PMCPMC13321978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.