Evidence map›Paper›PMID 41819578›Full record

ArticleBMJ open2026

CognIFied: protocol for a pilot randomised controlled trial of a culturally adapted, task-shifted compensatory cognitive training intervention for young adults with first-episode psychosis in Nigeria.

Abiodun O Adewuya, Adeniran Okewole, Bolanle Ola, Olabisi E Oladipo, Azizat Lebimoyo, Arit Esangbedo, Ayantunde Ayankola

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

7 authors.

Abiodun O AdewuyaLagos State University College of Medicine, Lagos, Nigeria abiodun.adewuya@lasucom.edu.ng.ORCID http://orcid.org/0000-0002-7611-6953
Adeniran OkewoleNeuropsychiatric Hospital, Abeokuta, Nigeria.
Bolanle OlaGriffith University Faculty of Health, Gold Coast, Queensland, Australia.
Olabisi E OladipoCentre for Mental Health Research and Initiative, Lagos, Nigeria.
Azizat LebimoyoLagos State University Teaching Hospital, Lagos, Nigeria.
Arit EsangbedoFederal Neuro Psychiatric Hospital, Yaba, Lagos, Nigeria.
Ayantunde AyankolaNeuropsychiatric Hospital, Abeokuta, Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCognitive impairment is present in the majority of individuals with first-episode psychosis (FEP) and is a strong predictor of long-term functional disability. Despite this, evidence-based cognitive interventions are rarely available in routine mental healthcare in low-income and middle-income countries, where most young people with psychosis reside. This protocol describes the CognIFied study, a pilot randomised controlled trial evaluating the feasibility and acceptability of a culturally adapted, task-shifted compensatory cognitive training (CCT) intervention for young adults with FEP in Nigeria. METHODS AND ANALYSIS: CognIFied is a multicentre, assessor-blind, parallel-group pilot randomised controlled trial with an embedded mixed-methods process evaluation. The study will recruit 180 young adults aged 18-30 years with Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)-defined FEP (onset within the past 5 years) and objective cognitive impairment from three public psychiatric hospitals in Nigeria. Participants will be randomised 1:1 to receive either culturally adapted CCT or an active control condition, Enhanced Recreational Therapy. Both interventions comprise 12 weekly group sessions lasting 60-90 min. CCT is delivered by trained psychiatric social workers using a manualised curriculum co-designed with young people with lived experience. Primary outcomes assess feasibility (recruitment, retention, intervention adherence), acceptability (Client Satisfaction Questionnaire-8) and intervention fidelity. Secondary outcomes include preliminary signals of effectiveness on global cognitive functioning (Brief Assessment of Cognition in Schizophrenia) and functional capacity (University of California, San Diego [UCSD] Performance-Based Skills Assessment), assessed at baseline and at 3, 6 and 12 months. Quantitative analyses will be descriptive and exploratory, supplemented by qualitative inquiry guided by Reach, Effectiveness, Adoption, Implementation, Maintenance (RE-AIM) and Consolidated Framework for Implementation Research frameworks and an exploratory economic evaluation. ETHICS AND DISSEMINATION: Ethical approval has been obtained from relevant institutional review boards. Findings will be disseminated through open-access publications, policy-focused stakeholder engagement and community dissemination co-led by a Youth Research Team. TRIAL REGISTRATION NUMBER: ISRCTN44794154.

Indexed as

Cognitive Behavioral TherapyCognitive DysfunctionCognitive TrainingPsychotic DisordersAdolescentAdultFeasibility StudiesFemaleHumansMaleMulticenter Studies as TopicNigeriaPilot ProjectsRandomized Controlled Trials as TopicYoung AdultClinical TrialCognitionPsychosocial InterventionSchizophrenia & psychotic disorders

Identifiers

PMID41819578
PMCPMC12983761

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.