Evidence map›Paper›PMID 41819482›Full record

ArticleHomeopathy : the journal of the Faculty of Homeopathy2026

Homeopathic Medicines for the Treatment of Acute Otitis Media: a Real-World Cohort Study on Recurrences and Antibiotic Prescriptions Compared to those with Conventional Treatments.

Norbert Banik, Kristina Hammerstiel, Sabine Niederle, Thorsten Reineke

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Article in Homeopathy : the journal of the Faculty of Homeopathy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Norbert BanikIndependent Consultant in Health Services Research and Epidemiology, München, Germany.
Kristina HammerstielDepartment of Homeopathy, Deutsche Homöopathie-Union GmbH & Co. KG, Karlsruhe, Germany.
Sabine NiederleDepartment of Homeopathy, Deutsche Homöopathie-Union GmbH & Co. KG, Karlsruhe, Germany.
Thorsten ReinekeDepartment of Clinical Research, Dr. Willmar Schwabe GmbH & Co. KG, Karlsruhe, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The study investigated the role of homeopathic medicines in daily treatment of uncomplicated (i.e., without need for an initial antibiotic prescription) acute otitis media (AOM). Recurrence rates and antibiotic prescriptions over 12 months were compared in patients initially prescribed either homeopathic medicines or medicines from one of three conventional therapeutic classes. Methods: This exploratory cohort study used real-world electronic health care data from the Disease Analyzer database (IQVIA). German patients of all ages diagnosed with AOM between 2010 and 2018 who were prescribed either homeopathic, nasal, otological medicines or non-opioid analgesics on the day of diagnosis or within 6 days thereafter were included. AOM recurrence was assessed using multivariable logistic regression; the number of antibiotic prescriptions was assessed using multivariable negative binomial regression. Key Results: A total of 113,983 of 745,372 patients diagnosed with AOM were eligible for analysis. Of these, 9.9% of patients initially received prescriptions for homeopathic medicines. In the total patient group, these prescriptions were associated with a slightly reduced risk of AOM recurrence compared with otological medicines (odds ratio, 1.17; statistically significant, Conclusion: The real-world data analyzed in this study reveal that homeopathic medicines play a relevant role in daily AOM treatment as a stand-alone therapy class. Additionally, the study yielded important methodological findings on prescription patterns in routine AOM care in Germany, with specific focus on the role of homeopathic medicines.

Indexed as

Anti-Bacterial AgentsHomeopathyMateria MedicaOtitis MediaAcute DiseaseAdolescentAdultAgedChildChild, PreschoolCohort StudiesFemaleGermanyHumansInfantMaleAnti-Bacterial AgentsMateria Medica

Identifiers

PMID41819482
PMCPMC13412704

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