Evidence map›Paper›PMID 41819063›Full record

ArticleMagyar onkologia2026

[rare subtype of kidney cancer - Pigmented microcystic chromophobe carcinoma].

Luca Szalai, Imola Adamik, Judit Betenbuk, Zsuzsa Sándor, Péter Dombóvári, Péter Tenke, Tibor Szarvas, Levente Kuthi

Abstract readCase ReportsEnglish Abstract
In one paragraph

Article in Magyar onkologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Luca SzalaiSebészeti és Molekuláris Patológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuthi.levente@oncol.hu.
Imola AdamikSebészeti és Molekuláris Patológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuthi.levente@oncol.hu.
Judit BetenbukSebészeti és Molekuláris Patológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuthi.levente@oncol.hu.
Zsuzsa SándorSebészeti és Molekuláris Patológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuthi.levente@oncol.hu.
Péter DombóváriUrológiai Daganatsebészeti Központ, Országos Onkológiai Intézet, Budapest, Hungary.
Péter TenkeUrológiai Daganatsebészeti Központ, Országos Onkológiai Intézet, Budapest, Hungary.
Tibor SzarvasUrológiai Klinika, Semmelweis Egyetem, Budapest, Hungary.
Levente KuthiSebészeti és Molekuláris Patológiai Osztály, Országos Onkológiai Intézet, Budapest, Hungary. kuthi.levente@oncol.hu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimChromophobe renal cell carcinoma (chRCC) is a morphologically heterogeneous tumor type, with one of its rarest forms being pigmented microcystic chromophobe carcinoma.

methodsIn our paper, we present the case of a 68-year-old man, in whom imaging studies identified a 32 mm kidney tumor.

resultsThe tumor was surgically removed, and pathological analysis revealed a cystic tumor with unusual morphology, composed of eosinophilic cells. Brown pigment and hemorrhage were present in the lumen of the cysts. Immunohistochemically, the tumor showed diffuse CD117, PAX8, and E-cadherin expression, with focal positivity for CK7 and CD10. GATA3, MelanA, HMB45, cathepsin K, CK20, chromogranin A, and synaptophysin reactions were negative. Chromosome 17 monosomy could not be detected using double-labeled HER2/cen17 chromogenic in situ hybridization. The patient recovered well after the operation and is currently under oncological care.

conclusionsTo the best of our knowledge, this is the first documented case of pigmented microcystic chromophobe carcinoma diagnosed in Hungary. The aim of this paper is primarily to raise awareness, and in the course of our work, we will review the morphological subtypes of chRCC and the differential diagnostic entities.

Indexed as

Biomarkers, TumorCarcinoma, Renal CellKidney NeoplasmsAgedHumansHungaryImmunohistochemistryMaleNephrectomyTomography, X-Ray ComputedBiomarkers, Tumor

Identifiers

PMID41819063
PMCPMC12990078

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.