[Dosimetric comparison of model-based and conventional calculation algorithms in high-dose-rate brachytherapy of head and neck tumours].

István Bodács, Zoltán Takácsi-Nagy, Tibor Major

Abstract readComparative StudyEnglish Abstract

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Article in Magyar onkologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 authors.

István BodácsCenter of Radiotherapy, National Institute of Oncology, Budapest, Hungary. major.tibor@oncol.hu.

Zoltán Takácsi-NagyCenter of Radiotherapy, National Institute of Oncology, Budapest, Hungary. major.tibor@oncol.hu.

Tibor MajorCenter of Radiotherapy, National Institute of Oncology, Budapest, Hungary. major.tibor@oncol.hu.

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No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate the effect of a model-based calculation algorithm that takes into account tissue inhomogeneities and real scattering conditions, on dose-volume parameters in brachytherapy for head and neck tumours.

methodsWe recalculated the treatment plans of twentyfour patients treated with brachytherapy using the modelbased Advanced Collapsed Cone Engine (ACE) algorithm. High-dose volumes in the target and volumes irradiated with lower doses were determined. We calculated the doses to the organs at risk for the small volumes receiving high doses and the average doses.

resultsThe conventional calculation algorithm calculated higher doses than ACE for almost all parameters. The difference was less than 1% for V100 and D90. Among the volumes enclosed by the isodose surfaces, the difference was greater between the high-dose volumes and the low-dose volumes. The doses to the mandible were 2-3% lower with ACE, while the doses to the skin were 4-7% lower. The difference to the salivary glands was between 5-8%, while the doses to the spinal cord were the same.

conclusionsWhen treating head and neck tumours, the traditional calculation algorithm overestimates the doses to the target volume and organs at risk. The introduction of the new calculation algorithm into clinical practice is not yet recommended.

Indexed as

AlgorithmsBrachytherapyHead and Neck NeoplasmsRadiotherapy Planning, Computer-AssistedFemaleHumansMandibleOrgans at RiskRadiotherapy DosageSalivary GlandsSkinSpinal Cord

Identifiers

PMID41819060

PMCPMC12990080

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