Evidence map›Paper›PMID 41818849›Full record

ArticlePsychoneuroendocrinology2026

Associations between adolescent adversity and young adult depression symptoms and allostatic load in Mexican-origin individuals.

Madeleine R Frazier, Amanda E Guyer, Paul D Hastings, Richard W Robins, Johnna R Swartz

Abstract read
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In one paragraph

Article in Psychoneuroendocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Madeleine R FrazierDepartment of Human Ecology, UC Davis, CA, USA. Electronic address: mrfrazier@ucdavis.edu.
Amanda E GuyerDepartment of Human Ecology, UC Davis, CA, USA; Center for Mind and Brain, UC Davis, CA, USA.
Paul D HastingsCenter for Mind and Brain, UC Davis, CA, USA; Department of Psychology, UC Davis, CA, USA.
Richard W RobinsDepartment of Psychology, UC Davis, CA, USA.
Johnna R SwartzDepartment of Human Ecology, UC Davis, CA, USA.

Funding

Mexican Family Culture &Substance Use Risk &ResilienceR01DA017902 · NIDA · UNIVERSITY OF CALIFORNIA DAVIS · PI CONGER, RAND DONALD, ROBINS, RICHARD W · 2005 to 2014
$11.6M
Neurobiological Reactivity, Allostatic Load and Depression in Mexican YouthR01MH098370 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GUYER, AMANDA E, HASTINGS, PAUL DAVID · 2012 to 2016
$2.8M
Risk and protective factors associated with the development of depression and allostatic load in young adults of Mexican origin.R01MH123530 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ROBINS, RICHARD W · 2021 to 2024
$1.6M
NIDA NIH HHS R01 DA017902NIMH NIH HHS R01 MH098370NIMH NIH HHS R01 MH123530
6 · The paper itself

Abstract

Childhood adversity increases risk for depression and higher allostatic load (AL), defined as long-term wear and tear on the body, and adolescence is an especially sensitive time for adversity to be biologically embedded. Individuals of Mexican origin may face multiple forms of adversities relating to their intersectional identities of ethnicity and class, including ethnic discrimination and economic hardship, the experience of which may further depend on sex. However, relatively little research has simultaneously assessed associations between these two types of adolescent adversity and outcomes of both young adult depression and AL longitudinally in Mexican-origin individuals. This preregistered study addressed these gaps in a longitudinal study of 208 Mexican-origin participants. Ethnic discrimination and economic hardship were assessed annually from ages 10-19 and AL and depression symptoms were assessed at age 26. Sex differences were also tested. Perceived discrimination in adolescence significantly predicted higher levels of depression at age 26 (β =.09, p = .045, R

Indexed as

Adverse Childhood ExperiencesAllostasisDepressionMexican AmericansAdolescentAdultChildFemaleHumansLongitudinal StudiesMalePovertyRacismStress, PsychologicalYoung AdultAdversityAllostatic loadDepressionEconomic hardshipMexican originPerceived discrimination

Identifiers

PMID41818849
PMCPMC13293614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.