Evidence map›Paper›PMID 41818202›Full record

ArticlePloS one2026

Enhancing recruitment and retention strategies in human tobacco research.

Laraib Mazhar, Nicolle Krebs, Sophia I Allen, Andrea L Hobkirk, Matthew Carrillo, Craig Livelsberger, Vicki Peters, Jonathan Foulds, Jessica M Yingst

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laraib MazharDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.ORCID https://orcid.org/0000-0002-7335-2336
Nicolle KrebsDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.
Sophia I AllenDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.ORCID https://orcid.org/0000-0002-1809-3749
Andrea L HobkirkDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.
Matthew CarrilloDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.
Craig LivelsbergerDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.ORCID https://orcid.org/0009-0004-6444-5102
Vicki PetersDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.
Jonathan FouldsDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.ORCID https://orcid.org/0000-0003-2296-0726
Jessica M YingstDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, Pennsylvania, United States of America.ORCID https://orcid.org/0000-0003-3028-668X

Funding

Mixed methods research to increase engagement and smoking abstinence among African Americans enrolled in Quitline text messaging servicesK01DA053410 · NIDA · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Sophia I. Allen · 2022 to 2026
$924k
NIDA NIH HHS K01 DA053410
6 · The paper itself

Abstract

introductionRecruitment and retention of study participants in tobacco research studies is challenging, and many studies are not able to meet desired sample sizes, particularly since the COVID-19 pandemic. This survey study explored tobacco users' motivations and expectations when considering participation in tobacco research and identifies common barriers to participation.

methodsParticipants were adult (21+) tobacco users recruited from a registry of potential research participants. In 2023, participants were emailed a survey to ascertain their motivations for participating in tobacco and health research, their expectations for participation, including compensation and barriers to participating. Means, medians, and proportions were calculated to describe the study population and outcomes. A binary variable for compensation importance was created and analyzed using logistic regression adjusting for demographic and tobacco use factors.

resultsParticipants (n = 267) had a mean age of 46.9 years (SD 11.47) and were 67.4% female, 91.0% White, and 3.4% Hispanic. The majority smoked cigarettes (84.3%), while 34.5% reported electronic cigarette use. Most participants (79.4%) indicated interest in tobacco research because they wanted to quit or reduce smoking/tobacco use. Anticipated median compensation for completing a visit lasting one hour with questionnaires was $25, or $50 if a blood draw was included. Two-thirds (66.7%, n = 178) of participants viewed compensation as important. Younger age was associated with the perceived importance of higher compensation (OR=0.971, 95% CI: 0.949-0.993, p = 0.011). The most commonly reported barriers to participation were related to current work schedule issues (41.6%) and not having the ability to take off work when the research center was open (38.6%).

conclusionMost participants were interested in tobacco and health research for the intrinsic benefit of quitting or reducing smoking. Removing scheduling and transportation issues with remote research when possible, may increase participation rates. When intrinsic benefit is not available, appropriate compensation should be utilized to boost recruitment and retention rates.

Indexed as

Patient SelectionAdultCOVID-19FemaleHumansMaleMiddle AgedMotivationSurveys and Questionnaires

Identifiers

PMID41818202
PMCPMC12981478

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.