Evidence map›Paper›PMID 41818154›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Atomistic simulations reveal the photoactivation mechanism of a carotenoid-binding photoreceptor.

Amanda Arcidiacono, Mattia Bondanza, Lorenzo Cupellini, Benedetta Mennucci

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Atomistic simulations reveal the photoactivation mechanism of a carotenoid-binding photoreceptor.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amanda ArcidiaconoDepartment of Chemistry and Industrial Chemistry, University of Pisa, Pisa 56124, Italy.ORCID 0009-0005-7325-759X
Mattia BondanzaDepartment of Chemistry and Industrial Chemistry, University of Pisa, Pisa 56124, Italy.ORCID 0000-0001-6254-3957
Lorenzo CupelliniDepartment of Chemistry and Industrial Chemistry, University of Pisa, Pisa 56124, Italy.ORCID 0000-0003-0848-2908
Benedetta MennucciDepartment of Chemistry and Industrial Chemistry, University of Pisa, Pisa 56124, Italy.ORCID 0000-0002-4394-0129

Funding

Next generationEU-PNRR ICSC-Centro Nazionale di Ricerca in High-Performance Computing Big Data and Quantum ComputingPRIN 2022 MUR 2022N8PBLM
6 · The paper itself

Abstract

The orange carotenoid protein (OCP) is a key photoreceptor in the photoprotection of cyanobacterial antenna complexes. Its peculiar activity is governed by a bound keto-carotenoid that functions both as a light sensor and an energy quencher. Upon blue light absorption, OCP transitions from an orange resting state (OCP

Indexed as

Bacterial ProteinsCarotenoidsPhotoreceptors, MicrobialBlue LightLightMolecular Dynamics SimulationProtein ConformationBacterial ProteinsCarotenoidsorange carotenoid protein, SynechocystisPhotoreceptors, Microbialenhanced samplingnonadiabatic dynamicsphotoisomerizationphotoreceptor protein

Identifiers

PMID41818154
PMCPMC12994174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.