Evidence map›Paper›PMID 41817843›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2026

Construction of novel pyrrole-derivative-based fluorescent platforms and development of polarity-sensitive probes for imaging lipid droplets in cells and zebrafish.

Jin-Hua Jiang, Yun-Hao Yang, Ying-Kun Liu, Ning Zhang, Jian-Yong Wang

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Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jin-Hua JiangSchool of Aeronautics, Shandong Jiaotong University, Jinan, 250357, Shandong, PR China. wjy@qlu.edu.cn.
Yun-Hao YangKey Laboratory of Paper Science and Technology of Ministry of Education, Faculty of Light Industry, State Key Laboratory of Green Papermaking and Resource Recycling, Qi Lu University of Technology (Shandong Academy of Sciences), Jinan, 250353, PR China.
Ying-Kun LiuKey Laboratory of Paper Science and Technology of Ministry of Education, Faculty of Light Industry, State Key Laboratory of Green Papermaking and Resource Recycling, Qi Lu University of Technology (Shandong Academy of Sciences), Jinan, 250353, PR China.
Ning ZhangKey Laboratory of Paper Science and Technology of Ministry of Education, Faculty of Light Industry, State Key Laboratory of Green Papermaking and Resource Recycling, Qi Lu University of Technology (Shandong Academy of Sciences), Jinan, 250353, PR China.
Jian-Yong WangKey Laboratory of Paper Science and Technology of Ministry of Education, Faculty of Light Industry, State Key Laboratory of Green Papermaking and Resource Recycling, Qi Lu University of Technology (Shandong Academy of Sciences), Jinan, 250353, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid droplets (LDs), serving as central hubs in lipid metabolism, exhibit dynamic changes closely associated with diseases such as obesity, diabetes, and cancer. Visualizing LDs is crucial for elucidating their role in biological mechanisms and facilitating early disease detection. Donor-acceptor (D-A) type fluorescent probes have been widely designed and employed for LD detection. In this study, we designed and constructed a pyrrole-based molecular scaffold with a symmetrical architecture. Through modulation of para-substituents, a series of novel fluorescent dyes (3a-e) were successfully synthesized. Experimental characterization revealed that the dimethylamino-modified dye 3e, characterized by a typical D-A-D structure, exhibits red emission (λ

Indexed as

Fluorescent DyesLipid DropletsPyrrolesAnimalsFluorescent Chemosensor CompoundsHumansMolecular StructureOptical ImagingZebrafishFluorescent Chemosensor CompoundsFluorescent DyesPyrrolesCell imagingFluorescent probeLipid dropletsPolarity-sensitive

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.