Evidence map›Paper›PMID 41817784›Full record

ArticleVeterinary research communications2026

Development of long-term antimicrobial resistance patterns of bovine mastitis pathogens in north-western Germany from 2005 to 2023.

Nadja Jessberger, Theresa Büthe, Bettina Schneider, Alina Kirse, Lothar Kreienbrock, Madeleine Plötz

Abstract read
In one paragraph

Article in Veterinary research communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Isolation, characterization, andFrontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nadja JessbergerInstitute for Food Quality and Food Safety, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, Hanover, 30173, Germany. Nadja.Jessberger@tiho-hannover.de.
Theresa BütheInstitute for Food Quality and Food Safety, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, Hanover, 30173, Germany.
Bettina SchneiderInstitute of Biometry, Epidemiology and Information Processing, University of Veterinary Medicine Hannover, Bünteweg 2, Hanover, 30559, Germany.
Alina KirseInstitute of Biometry, Epidemiology and Information Processing, University of Veterinary Medicine Hannover, Bünteweg 2, Hanover, 30559, Germany.
Lothar KreienbrockInstitute of Biometry, Epidemiology and Information Processing, University of Veterinary Medicine Hannover, Bünteweg 2, Hanover, 30559, Germany.
Madeleine PlötzInstitute for Food Quality and Food Safety, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, Hanover, 30173, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spread of antimicrobial resistances is a global threat. This study provides a retrospective, explorative analysis of bovine mastitis samples from 2005 to 2023, regarding the antimicrobial resistance patterns of the corresponding pathogens. 41.8% of the tested samples were positive for mastitis pathogens. Regarding the occurrence of antimicrobial resistances, 18,623 tests were analysed in total, comprising the 13 most frequently identified bacterial pathogens. The highest percentage of total antimicrobial resistant samples was detected for Proteus spp. (55.2%), Bacillus spp. (44.3%) and Citrobacter freundii (40.8%), while the lowest percentage was found for Staphylococcus aureus (7.1%), Trueperella pyogenes (6.1%), and Streptococcus dysgalactiae (3.1%). Furthermore, S. uberis, S. dysgalactiae, and T. pyogenes showed an overall linear decrease of antimicrobial resistant samples from 2005 to 2023. Trends of increased resistances were also identified for individual pathogen-antimicrobial combinations. To date, long-term, large-scale studies like this have rarely been conducted, but they are of particular importance in identifying trends in the shift of antimicrobial resistances among mastitis pathogens. The results of such routine diagnostic data must be viewed with caution, as they cannot be readily extrapolated to the entire dairy population. Nevertheless, these findings emphasize the necessity of unambiguous pathogen identification, including susceptibility testing, prior to antimicrobial administration. Alternative therapy methods also become increasingly important, as well as proper farm management and hygiene to prevent infections from the beginning.

Indexed as

Anti-Bacterial AgentsBacteriaDrug Resistance, BacterialMastitis, BovineAnimalsCattleFemaleGermanyMicrobial Sensitivity TestsRetrospective StudiesAnti-Bacterial AgentsAntimicrobial useDairy cowsEscherichia coliNon-aureus staphylococci and mammaliicocciSecondary data useStreptococcus uberis

Identifiers

PMID41817784
PMCPMC12982301

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.