SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026
Isolated frontosphenoidal suture synostoses: report of two cases and literature review.
Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAnterior plagiocephaly is most commonly attributed to unilateral coronal synostosis. However, isolated premature fusion of the frontosphenoidal suture (FSC) represents a rare and often misdiagnosed cause due to its overlapping clinical presentation. Accurate diagnosis is essential, as treatment strategies and prognoses differ significantly.
objectivesTo present a comprehensive literature review of FSC and to report two novel clinical cases-one managed with open fronto-orbital advancement and the other with endoscopic suturectomy.
methodsA systematic review of reported FSC cases was performed and supplemented by two patients treated at our institution. Diagnosis was established using cranial computed tomography (CT) with three-dimensional (3D) reconstruction. The first patient underwent open fronto-orbital advancement, while the second was treated with early endoscopic suturectomy.
resultsIn both patients, isolated fusion of the frontosphenoidal suture was confirmed with preservation of the coronal sutures. The first patient, diagnosed at 9 months of age, presented with typical signs of anterior plagiocephaly without the Harlequin sign, and underwent open surgery with excellent postoperative craniofacial symmetry. The second patient, diagnosed earlier due to subtle craniofacial asymmetry, was treated endoscopically with favorable aesthetic results and no postoperative complications.
conclusionsFSC represents a rare and underrecognized cause of anterior plagiocephaly. High clinical suspicion is required in cases of atypical cranial asymmetry with open coronal sutures. Cranial CT with 3D reconstruction is essential for accurate diagnosis and identification of the suture involvement. Both open and endoscopic surgical approaches can achieve satisfactory outcomes when appropriately indicated.
Indexed as
Identifiers
41817755What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.