Evidence map›Paper›PMID 41817735›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2026

Long-term outcomes in physical function and quality of life after traumatic thoracolumbar A3/A4 fractures: a comparison of conservative versus surgical management.

Anna Silke Sienema, Inge H F Reininga, Joost Hoekstra

Abstract readComparative Study
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Anna Silke SienemaDepartment of Trauma Surgery, University of Groningen, University Medical Center Groningen, HPC BA13, Hanzeplein 1, Groningen, 9713 GZ, The Netherlands. a.s.sienema@umcg.nl.ORCID http://orcid.org/0009-0009-0864-8665
Inge H F ReiningaDepartment of Trauma Surgery, University of Groningen, University Medical Center Groningen, HPC BA13, Hanzeplein 1, Groningen, 9713 GZ, The Netherlands.
Joost HoekstraDepartment of Trauma Surgery, University of Groningen, University Medical Center Groningen, HPC BA13, Hanzeplein 1, Groningen, 9713 GZ, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo provide insight into the recovery rates of patient-reported outcome measures (PROMs) in terms of physical functioning and health-related quality of life (QoL) in patients with an A3/A4 thoracolumbar vertebral fracture, compared to the general population. Additionally, differences in outcomes between conservatively and surgically treated patients were assessed.

methodsA retrospective cohort study with cross-sectional follow-up including patients with thoracolumbar A3/A4 vertebral fractures in a level 1 trauma center between 2010 and 2020. SMFA-NL was used to evaluate physical functioning, and EQ-5D was used to assess QoL. Outcomes were compared with normative data from the Dutch population. Patient-reported outcomes and complication rates were reported for each treatment type. Recovery was defined as reaching the lower limit of the 95% confidence interval of the normative data in all outcome measures.

resultsPROMs were available for 98 (37%) of the eligible patients with a median follow-up of 4.5 (IQR = 5.6) years. No significant differences in physical functioning or QoL were found between conservatively and surgically treated patients. The following non-recovery rates were found in the conservatively treated patients: physical functioning = 56–74%, QoL = 48% and in the surgically treated patients: physical functioning = 77–80%, QoL = 45%. Surgically treated patients showed significantly higher complication rates than conservatively treated patients.

conclusionThoracolumbar A3 and A4 fractures are associated with long-term reduced physical functioning and quality of life compared with the general population, regardless of treatment strategy. Both surgically and conservatively treated patients showed significantly low recovery rates in comparison with their peers from the general population.

Indexed as

Conservative TreatmentLumbar VertebraeQuality of LifeSpinal FracturesThoracic VertebraeAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNetherlandsPatient Reported Outcome MeasuresRecovery of FunctionRetrospective StudiesPatient-reported outcomePhysical functioningQuality of lifeThoracolumbar A3/A4 fracturesVertebral fractures

Identifiers

PMID41817735
PMCPMC12982316

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.