Evidence map›Paper›PMID 41817667›Full record

ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2026

The impact of a two-stage newborn hearing screening protocol for early diagnosis of hearing loss.

Rita Malesci, Chiara Quatrano, Valeria Del Vecchio, Giovanni Freda, Antonella Castaldi, Francesco Nunziata, Pietro Buono, Anna Rita Fetoni

Abstract read
In one paragraph

Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Rita MalesciAudiology Section, Department of Neuroscience and Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Chiara QuatranoAudiology Section, Department of Neuroscience and Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Valeria Del VecchioHearing and Balance Unit, Federico II University Hospital, Naples, Italy.
Giovanni FredaAudiology Section, Department of Neuroscience and Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Antonella CastaldiAudiology Section, Department of Neuroscience and Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Francesco NunziataDepartment of Pediatrics, Santobono Pausilipon Hospital, Naples, Italy.
Pietro BuonoDepartment of Maternal and Child Health, General Directorate for Health, Naples, Italy.
Anna Rita FetoniAudiology Section, Department of Neuroscience and Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Early detection and prompt intervention of permanent hearing impairment (PHI) can only be achieved through universal newborn hearing screening (UNHS) in the first month of life. The most common screening protocols worldwide involve a combined approach with transient evoked otoacoustic emissions (TEOAEs) and automated auditory brainstem response (AABR). Our study aims to evaluate the proportion of infants with PHI in a population with discordant outcome TEOAEs/AABR through audiological follow-up. Methods: The present study enrolled 637 healthy babies who failed TEOAEs at birth and were referred for a secondary level audiological evaluation with TEOAEs and AABR. Ninety babies with discordant outcome (TEOAEs refer/AABR pass) underwent audiological retest adding tympanometry and clinical click-evoked auditory brainstem response. Results: PHI was confirmed in 12 babies (7 bilaterally and 5 unilaterally) and the degree was mild to moderate in 8 and in 4 babies, respectively. There were no risk factors for delayed onset of hearing loss in half of PHI. Conclusions: The discordant TEOAEs refer/AABR pass suggests that follow-up should be recommended independently of risk factors for PHI to avoid misleading diagnosis of mild or late-onset hearing loss.

Indexed as

Hearing LossHearing TestsNeonatal ScreeningEarly DiagnosisEvoked Potentials, Auditory, Brain StemFemaleHumansInfant, NewbornMaleOtoacoustic Emissions, Spontaneousautomated auditory brainstem responsehearing losstransient evoked otoacoustic emissionsuniversal newborn hearing screening

Identifiers

PMID41817667
PMCPMC12994100

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.