ArticleJACC. Case reports2026
Large PPM Lead-Associated Thrombus in a JAK2-Positive Patient.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntracardiac thrombi are a complication of cardiac implantable electronic devices (CIEDs) and device leads. While the risk of pulmonary embolism exists, clinically significant pulmonary embolism is rare, possibly because of low embolism rates or small embolic material. Larger thrombi pose greater concern, yet guidelines regarding investigation and management are limited. CASE SUMMARY: We describe the investigation of a large and mobile CIED-related thrombus in a patient with previous infectious endocarditis and myeloproliferative neoplasm, including serial multimodal imaging assessment, individualized management considerations, and anticoagulation. DISCUSSION: Large intracardiac thrombi have the potential to cause significant morbidity and mortality. The investigation and management of large intracardiac thrombi is an area of cardiology that is largely evidence free. Current literature suggests strategies may involve medical or procedural approaches, but evidence is restricted to case reports. TAKE-HOME MESSAGES: Large intracardiac CIED-related thrombi remain clinically significant but poorly studied. Anticoagulation is the mainstay of treatment, however decisions are highly individualized.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.