ArticleTurkish journal of medical sciences2026
Developing liposomal and ethosomal formulations with potent antioxidant and cytotoxic effects: unleashing the power of
Article in Turkish journal of medical sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background/aim: Materials and methods: A total of 10 extracts were prepared from the plant's aerial parts using ethanol concentrations ranging from 10% to 99.9%. The DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) radical scavenging tests were used to assess the antioxidant properties of the extracts. Cytotoxic effects were assessed using the MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide) method on human colon cancer, cervical cancer, and breast cancer cell lines. The most active extract was further analyzed for its phenolic composition using high-performance liquid chromatography. This extract was then encapsulated in liposomes and ethosomes, known as nanocarrier systems, to enhance and prolong its efficacy. Results: The 99.9% ethanol extract exhibited strong DPPH scavenging activity with an IC Conclusion: This study shows that absolute ethanol is a highly effective solvent for obtaining bioactive extracts from
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