Evidence map›Paper›PMID 41816707›Full record

ArticleACS applied nano materials2026

Short Segments of Electrospun Nanofibers Loaded with Curcumin Can Protect the Cells in Spheroids against Oxidative Stress.

Yuxuan Meng, Min Hao, Younan Xia

Abstract read
In one paragraph

Article in ACS applied nano materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yuxuan MengSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID https://orcid.org/0009-0008-1373-1255
Min HaoThe Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, Georgia 30332, United States.ORCID https://orcid.org/0009-0006-3517-3392
Younan XiaSchool of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332, United States.ORCID https://orcid.org/0000-0003-2431-7048

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxidative stress in damaged or inflamed tissues presents a major barrier to the efficacy of cell-based therapies by impairing cell viability, function, and engraftment. Herein, we demonstrate a nanofiber-integrated three-dimensional spheroid platform that delivers Curcumin (Cur), a natural antioxidant, for cellular protection. Cur can be encapsulated in electrospun polycaprolactone (PCL) fibers, which are processed into short segments and coassembled with human mesenchymal stem cells to form spheroids. The integrated fibers enable a two-phase release profile of Cur while preserving spheroid morphology and maintaining cell organization. Under H

Indexed as

antioxidant therapycellular protectioncurcumin deliveryelectrospun fibersoxidative stress

Identifiers

PMID41816707
PMCPMC12973261

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.