Evidence map›Paper›PMID 41816648›Full record

ArticleHealth science reports2026

Prescribed Medication Burden by Tobacco Smoking and E-Cigarette Use Status.

Yusuff Adebayo Adebisi, Leonard Ighodalo Uzairue, Rachael Oluwatoyosi Farayola, Eseosa Iyagbaye, Christian Joseph N Ong, Akpevwe Emmanuella Benson, Ngoni Veddie Muzondo, Adeyemo Deborah Temitope

Abstract read
In one paragraph

Article in Health science reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yusuff Adebayo AdebisiCollege of Social Sciences University of Glasgow Glasgow UK.ORCID https://orcid.org/0000-0002-2381-0984
Leonard Ighodalo UzairueFaculty of Health and Life Sciences De Montfort University, The Gateway Leicester UK.
Rachael Oluwatoyosi FarayolaCentre for Lifestyle Medicine and Behaviour, School of Sport Exercise and Health Sciences Loughborough University Loughborough UK.
Eseosa IyagbayeChronic Disease Mate for Africa (CDMA) Benin City Nigeria.
Christian Joseph N OngDepartment of Biology, College of Science De La Salle University Manila Philippines.
Akpevwe Emmanuella BensonFaculty of Pharmacy University of Benin Benin City Edo Nigeria.
Ngoni Veddie MuzondoDepartment of Pharmaceutical Technology Harare Institute of Technology Harare Zimbabwe.
Adeyemo Deborah TemitopeFaculty of Pharmaceutical Sciences University of Ilorin Ilorin Nigeria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Tobacco smoking is a major driver of chronic disease, and e-cigarette use is increasingly common, yet their associations with prescribed medication burden remain unclear. Methods: We analysed data from 1657 adults aged ≥ 16 years who completed a nurse visit in the Health Survey for England 2021. Smoking and e-cigarette status were categorized into four mutually exclusive groups: never users, current smokers, current exclusive e-cigarette users, and ex-smokers. Prescribed medication use in the past 7 days was verified by nurses and grouped into seven BNF-based therapeutic categories: cardiovascular, metabolic, respiratory, pain and anti-inflammatory, gastrointestinal, mental health, and anti-infectives. Overall, medication burden was categorized as none, one, two, or three or more prescribed medicines. Generalized ordered logistic regression estimated associations with overall burden, and Firth penalized logistic regression examined therapeutic categories, adjusting for age, sex, education, and area-level deprivation. Sensitivity analyses restricted the sample to adults aged ≥ 45 years. Results: Ex-smokers reported the highest medication burden, with 20.3% prescribed three or more medicines compared with 8.6% of never users, 10.9% of current smokers, and 12.2% of current e-cigarette users ( Conclusions: Ex-smokers had the highest medication burden compared with never users, which may partly reflect reverse causation, whereby illness and associated treatment prompt smoking cessation, though residual effects of prior smoking cannot be excluded. Current smokers showed no significant excess burden, possibly due to a "healthy smoker" effect, and e-cigarette use was not associated with overall burden compared with never users, although it was linked to greater use of pain and anti-inflammatory medicines.

Indexed as

e‐cigarette useex‐smokersHealth Survey for Englandmedication burdenprescribing patternspublic healthTobacco smoking

Identifiers

PMID41816648
PMCPMC12971602

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.