Evidence map›Paper›PMID 41816567›Full record

ArticleJournal of gastrointestinal oncology2026

Clinical model for predicting overall survival outcomes in individuals with hepatocellular carcinoma: a retrospective cohort analysis.

Maher Hendi, Ying-Ying Chen, Bin Zhang, Yi-Fan Wang, Xiu-Jun Cai

Abstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Maher HendiDepartment of Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Ying-Ying ChenDepartment of Endoscopy Center, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Bin ZhangDepartment of Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yi-Fan WangDepartment of Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Xiu-Jun CaiDepartment of Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The prognostic factors for survival outcomes in patients with hepatocellular carcinoma (HCC) are not well defined. This study aimed to identify the prognostic factors for HCC and to construct a predictive nomogram model. Methods: A total 165 patients with HCC were identified between 25 January 2010 and 10 November 2021. Independent prognostic factors were identified using univariable and multivariable Cox regression analyses. A nomogram was constructed to predict the patient survival rate. The concordance index (C-index), area under the curve (AUC), and calibration curves were used to assess the predictive accuracy and discrimination of the model. Decision curve analysis was used to confirm the clinical utility of the nomogram. Results: A total of 165 patients were randomly selected retrospectively. Univariable and multivariable analyses revealed that body mass index, albumin, carbohydrate antigen 19-9 (CA19-9), tumor size, and tumor size, lymph node, metastasis (TNM) stage were independent factors for predicting patient survival. We constructed a 1-, 3-, and 5-year survival rate prediction clinical model by using these independent prognostic factors, which yielded C-indexes of 0.838, 0.798 and 0.725, respectively. On the basis of the AUCs and calibration curve and decision curve analyses, we concluded that the prognostic model for HCC exhibited excellent performance. Conclusions: The clinical model demonstrated good calibration, discrimination, clinical utility, and practical decision-making effects for the outcomes of patients with HCC. These findings may help oncologists and surgeons make better clinical decisions.

Indexed as

Hepatocellular carcinoma (HCC)least absolute shrinkage and selection operator (LASSO)nomogramprognostic factorssurvival prediction model

Identifiers

PMID41816567
PMCPMC12971997

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.