Evidence map›Paper›PMID 41816511›Full record

ArticleStroke (Hoboken, N.J.)2026

Efficacy Assessment of the TIMSO Microcatheter for Endovascular Thrombectomy in the Treatment of Acute Ischemic Stroke.

Ying Jiang, Lan Dong, Shao-Hui Shen, Ruan-Feng Wang, Qin-Qin Shu, Yi-Lin Liu, Jie-Qing Wan, Chun-Lang Hong, Ning Zhang, Yan-Jun Guan

Abstract read
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In one paragraph

Article in Stroke (Hoboken, N.J.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ying JiangDepartment of Neurosurgery, Cerebrovascular Diseases Center, Renji Hospital (Y.J., J.-Q.W.), Shanghai Jiao-tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-9800-6432
Lan DongDepartment of Emergency Medicine (L.D.), Changzheng Hospital of Naval Medicine University, Shanghai, China.ORCID https://orcid.org/0009-0004-2220-5397
Shao-Hui ShenVIP Department, East Hospital affiliated to Tongji University, Shanghai, China (S.-H.S.).ORCID https://orcid.org/0009-0004-5190-3178
Ruan-Feng WangDepartment of Research and Development, Shanghai HaoFeng Medical Technology Co, Ltd, China (R.-F.W., C.-L.H.).
Qin-Qin ShuDepartment of Emergency Medicine, Shanghai No. 4 People's Hospital affiliated to Shanghai Tongji University School of Medicine, China (Q.-Q.S.).ORCID https://orcid.org/0000-0002-0814-0070
Yi-Lin LiuDepartment of Nursing (Y.-L.L.), Changzheng Hospital of Naval Medicine University, Shanghai, China.
Jie-Qing WanDepartment of Neurosurgery, Cerebrovascular Diseases Center, Renji Hospital (Y.J., J.-Q.W.), Shanghai Jiao-tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0009-0003-3469-7408
Chun-Lang HongDepartment of Research and Development, Shanghai HaoFeng Medical Technology Co, Ltd, China (R.-F.W., C.-L.H.).
Ning ZhangDepartment of Neurosurgery, Shanghai Fengxian District Central Hospital, Shanghai Jiao Tong University Affiliated to Sixth People's Hospital South Campus, China (N.Z.).
Yan-Jun GuanDepartment of Comprehensive Surgery, Shanghai Rui-Jin Hospital (Y.-J.G.), Shanghai Jiao-tong University School of Medicine, Shanghai, China.ORCID https://orcid.org/0000-0001-6828-655X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndovascular thrombectomy is an effective treatment for acute ischemic stroke, and accurate determination of thrombus length (TL) remains pivotal to successful endovascular thrombectomy. However, to date, no modality could estimate the TL with sufficient efficiency, especially in the emergent setting. In the current study, we presented a novel microcatheter design known as the Tip-End Multi-Side Orifices (TIMSO) microcatheter, which could provide real-time TL assessment.

methodsThe efficacy of the TIMSO was initially validated in an endovascular simulator with continuous saline circulation. After the TIMSO passed the sham thrombus, colored saline was injected through the TIMSO. The length of the ink defect region was integrated with the sham TL. Subsequently, in the live swine acute ischemic stroke model, the efficacy of TIMSO was further evaluated under digital subtraction angiography.

resultsIn the simulation, a strong positive correlation was observed between the actual TL and the length indicated by the TIMSO (n=20,

conclusionsConclusively, the TIMSO microcatheter could facilitate real-time assessment of TL during endovascular thrombectomy. Furthermore, TISMO has the capacity to discern special embolization scenarios. These characteristics of TIMSO have the potential to contribute to the facilitation of endovascular thrombectomy in future clinical practice.

Indexed as

cathetersischemic strokestentsthrombectomy

Identifiers

PMID41816511
PMCPMC12959441

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.