Evidence map›Paper›PMID 41816469›Full record

ArticleJournal of thoracic disease2026

The clinical relevance of postoperative routine contrast swallow following esophagectomy.

Cezanne D Kooij, Karlijn H E Smitt, B Feike Kingma, Lucas Goense, Sylvia van der Horst, Emke M J M van den Broek, Gabriella Canu, Jelle P Ruurda, Richard van Hillegersberg

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cezanne D KooijDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-5985-0075
Karlijn H E SmittDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
B Feike KingmaDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Lucas GoenseDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Sylvia van der HorstDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Emke M J M van den BroekDepartment of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Gabriella CanuDepartment of Otorhinolaryngology/Head and Neck Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Jelle P RuurdaDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.
Richard van HillegersbergDepartment of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Limited evidence exists regarding the role of the routine contrast swallow in determining the safety of initiating oral intake following esophagectomy. Therefore, this study evaluated its clinical relevance in decision-making regarding oral intake. Methods: A descriptive, observational, single-center study included esophageal cancer patients who underwent esophagectomy with gastric conduit reconstruction between March 2019 and March 2021. Patients were kept nil by mouth until postoperative day (POD) 3 and began oral intake from POD 4 if the contrast swallow was normal. The primary outcome was routine use (POD 2-6) of the contrast swallow and its impact on oral intake decisions. Predictors of an abnormal contrast swallow were explored using logistic regression. Results: A contrast swallow was routinely performed in 80 of 110 patients (73%), of which 48 (44%) had a normal contrast swallow, while 32 (29%) had an abnormal contrast swallow. Ultimately, in 28 patients (25%), findings of the contrast swallow led to a decision to delay oral intake. All abnormal contrast swallows (n=32) involved aspiration (n=30, 94%) or laryngeal penetration (n=2, 6%). Aspiration occurred alongside delayed gastric conduit emptying in 2 cases, and anastomotic leakage was suspected in 2 others but not confirmed on computed tomography (CT) scan. No statistically independent predictors of an abnormal contrast swallow were identified in multivariable analysis. Conclusions: Routine contrast swallow following esophagectomy led to withholding oral intake in 25% of cases. Future research should explore a more selective approach in specific patient categories.

Indexed as

Contrast swallowenhanced recovery after surgery (ERAS)esophagectomy

Identifiers

PMID41816469
PMCPMC12972813

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.