Evidence map›Paper›PMID 41816456›Full record

ArticleJournal of thoracic disease2026

Research frontiers and emerging trends in sex and gender differences in chronic obstructive pulmonary disease: a bibliometric analysis.

Qianqian Li, Sihan Zhang, Jiankang Jiang, Hui Li, Zegeng Li, Jie Zhu, Jiabing Tong, Fan Wu

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qianqian Li *First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, China.
Sihan Zhang *First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, China.
Jiankang JiangSchool of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China.
Hui LiAcademy of Acupuncture and Massage, Anhui University of Chinese Medicine, Hefei, China.
Zegeng LiFirst Clinical Medical College, Anhui University of Chinese Medicine, Hefei, China.
Jie ZhuSchool of Chinese and Western Medicine, Anhui University of Chinese Medicine, Hefei, China.
Jiabing Tong *First Clinical Medical College, Anhui University of Chinese Medicine, Hefei, China.
Fan Wu *School of Chinese Medicine, Anhui University of Chinese Medicine, Hefei, China.ORCID https://orcid.org/0009-0002-2680-4296

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Numerous studies have examined sex and gender differences in chronic obstructive pulmonary disease (COPD), highlighting their roles in disease susceptibility, hormonal regulation, and inflammation. However, research often conflates sex and gender, and gaps remain in tailored therapies and genetic mechanisms. This study, therefore, employs bibliometric analysis to map the evolution and landscape of this research field. Methods: The authors systematically retrieved literature from the Web of Science Core Collection database, focusing on publications addressing gender differences in COPD between January 1, 2015, and March 4, 2025. The search strategy used the following Boolean query: [TS= ("COPD" OR "Chronic Obstructive Pulmonary Disease") AND ("gender" OR "male" OR "female") NOT ("animal model" OR "cell culture")], adhering to Web of Science Core Collection search syntax rules that ignore case sensitivity but require logical operator capitalisation. Subsequently, bibliometric analyses were performed using CiteSpace 6.3.R1 and VOSviewer 1.6.20. Results: The search identified 493 publications, and the annual output showed a steady rise. De Miguel-Díez J was the most productive author, and CIBER was the leading institution. High-frequency keywords included COPD, respiratory system, gender differences, and prevalence. Recent focus shifted to gender differences and COPD comorbidities. Conclusions: Investigations into sex and gender-specific COPD manifestations have grown in recent years, engaging a growing scientific community. This work systematically synthesises pivotal research trajectories and novel mechanistic insights into gender-differentiated COPD pathology. Future therapeutic strategies for COPD may target the role of sex hormones in pulmonary pathophysiology. The comprehensive summary provides an informative theoretical foundation for researchers and clinical providers and is key to future research tools in this field.

Indexed as

Chronic obstructive pulmonary disease (COPD)CiteSpacerespiratory systemsexVOSviewer

Identifiers

PMID41816456
PMCPMC12972932

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.