ArticleJournal of thoracic disease2026
Integration of MSK-FI and clinical variables to predict postoperative complications after esophagectomy.
Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Background: Frailty is associated with adverse clinical outcomes and is recognized as an important predictor of prognosis. Yet, practical frailty-based tools to assess the risk of postoperative complications after radical esophagectomy are still inadequate. The aim of this study was to evaluate the predictive performance of the Memorial Sloan Kettering-Frailty Index (MSK-FI) and to establish a more comprehensive model for forecasting postoperative complications in this patient population. Methods: We retrospectively analyzed 410 patients who underwent radical esophagectomy between 2022 and 2023. Preoperative frailty status of these patients was calculated using MSK-FI. Patients were accordingly classified as frail (MSK-FI ≥2, n=86) or non-frail (MSK-FI <2, n=324). A predictive nomogram was subsequently conducted by incorporating clinical and surgical characteristics. Results: Compared with the non-frail group, patients in the frail group had significantly higher rates of severe postoperative complications (26.74% Conclusions: Preoperative frailty status is associated with an increased risk of adverse perioperative outcomes in patients after radical esophagectomy. The integration of MSK-FI and clinical characteristics in nomogram provides a practical tool for predicting severe postoperative complications.
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