Evidence map›Paper›PMID 41816391›Full record

ArticleJournal of thoracic disease2026

Clinical classification of chronic obstructive pulmonary disease with invasive pulmonary aspergillosis: a retrospective study.

Luguang Wu, Tiantian Tang, Xiaoping Huang, Zhulin Xiao, Jiabin Ding, Ye Zhuang, Tianyuan Wang, Dan Long, Juan Yan, Linjie Huang and 2 more

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Luguang Wu *Department of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.
Tiantian Tang *Department of Respiratory and Critical Care Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Xiaoping Huang *Department of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.
Zhulin XiaoDepartment of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.
Jiabin DingDepartment of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.
Ye ZhuangDepartment of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.
Tianyuan WangDepartment of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.
Dan LongDepartment of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.
Juan YanDepartment of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.
Linjie HuangDepartment of Respiratory and Critical Care Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Shanping JiangDepartment of Respiratory and Critical Care Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Jianting ShiDepartment of Respiratory Medicine, Shenshan Medical Center, Memorial Hospital of Sun Yet-sen University, Shanwei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with chronic obstructive pulmonary disease (COPD) complicated by invasive pulmonary aspergillosis (IPA) have high mortality and significant clinical heterogeneity. However, systematic classification criteria are currently lacking. To address this, our study proposes a clinical classification system specifically for COPD-IPA, based on its distinct clinical manifestations and pulmonary imaging features. Methods: We performed a retrospective analysis of clinical and radiological features in patients diagnosed with COPD-IPA during hospitalization from 2008 to 2024 to develop a novel clinical classification system. Demographic characteristics, laboratory parameters, radiologic manifestations, and prognosis were compared across the identified subtypes. Results: The study cohort comprised 63 COPD-IPA patients, who were predominantly elderly males (mean age: 70.9±8.7 years; 95.2% male). A novel classification system defined five distinct subtypes: (I) the fulminant type (3/63, 4.8%), which progressed rapidly to respiratory failure [partial pressure of arterial oxygen (PaO Conclusions: The five-subtype classification system established in this study delineates the heterogeneity of COPD-IPA and provides a novel framework to guide precise clinical management.

Indexed as

Chronic obstructive pulmonary disease (COPD)clinical classificationimaging characteristicsinvasive pulmonary aspergillosis (IPA)phenotypes

Identifiers

PMID41816391
PMCPMC12972763

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.