Evidence map›Paper›PMID 41816372›Full record

ReviewJournal of thoracic disease2026

Extension of the minimally invasive pectus repair to adult patients: strategies for success.

Nour B Odeh, Abdulrahman Senjab, Rawan M Zeineddine, Ahmed E Khedr, Juan M Farina, Amjed A Al, Jesse J Lackey, Dawn E Jaroszewski

Abstract readReview
In one paragraph

Review in Journal of thoracic disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nour B Odeh *Department of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.ORCID https://orcid.org/0000-0002-9036-9906
Abdulrahman Senjab *Department of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.
Rawan M ZeineddineDepartment of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.ORCID https://orcid.org/0000-0002-9896-3758
Ahmed E KhedrDepartment of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.
Juan M FarinaDepartment of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.ORCID https://orcid.org/0000-0002-5824-8485
Amjed A AlDepartment of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.
Jesse J LackeyDepartment of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.
Dawn E JaroszewskiDepartment of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.ORCID https://orcid.org/0000-0002-5650-0691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pectus excavatum (PE) is the most common congenital deformity of the anterior chest wall and is increasingly recognized as a clinically relevant condition in adult patients. While minimally invasive repair of pectus excavatum (MIRPE) is well established in pediatric and adolescent populations, early attempts to apply this technique in adults were associated with higher complication rates. These challenges were largely attributed to increased chest wall rigidity, more severe and asymmetric deformities, and greater mechanical forces acting on intrathoracic support bars. Over the past two decades, however, progressive refinements in surgical technique, bar stabilization, and perioperative management have enabled the safe expansion of MIRPE to adult populations. This review summarizes the contemporary literature on MIRPE in adults, focusing on patient selection, technical considerations, perioperative strategies, and reported outcomes. Adult MIRPE presents distinct technical challenges and frequently requires modifications such as routine thoracoscopic guidance, forced sternal elevation, reinforcement of intercostal spaces, use of multiple bars, cross-bar configurations, and enhanced bar fixation techniques to achieve durable correction. These technical adaptations have contributed to reductions in bar displacement, recurrence, and major complications in more recent series. Postoperative pain management remains a critical component of adult repair, and the adoption of multimodal analgesic protocols, including intercostal nerve cryoablation, has been associated with reduced opioid requirements and shorter hospital length of stay. Contemporary reports from experienced, high-volume centers demonstrate consistent improvements in patient-reported quality of life (QoL), symptom burden, and cosmetic satisfaction following adult MIRPE. Improvements in cardiopulmonary function have been described in selected patients, particularly when complete anatomic correction is achieved, although objective physiologic benefits remain variable across studies. Adult MIRPE is technically demanding, and outcomes appear closely linked to surgeon experience and institutional volume. With careful patient selection and modern surgical strategies, MIRPE can be performed safely and effectively in adult patients, including those over 30 years of age. Further prospective studies focused on adult populations are needed to better define long-term outcomes and durability following bar removal.

Indexed as

Adult minimally invasive repair of pectus excavatum (MIRPE)chest wall deformitypectus excavatum (PE)technique modification

Identifiers

PMID41816372
PMCPMC12972870

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.