Evidence map›Paper›PMID 41816336›Full record

SynthesisFrontiers in immunology2026

Systematic review and meta-analysis of PET-based prognostic metrics in CAR-T treatment of DLBCL.

Chirong Long, Xu Liu, Hanqi Fang, Haomiao Qi, Chunyu Ma, Huaizhi Wang, Zhenghong Li

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chirong LongSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu, Anhui, China.
Xu LiuSchool of clinical medicine, Bengbu Medical University, Bengbu, Anhui, China.
Hanqi FangSchool of clinical medicine, Bengbu Medical University, Bengbu, Anhui, China.
Haomiao QiSchool of clinical medicine, Bengbu Medical University, Bengbu, Anhui, China.
Chunyu MaSchool of clinical medicine, Bengbu Medical University, Bengbu, Anhui, China.
Huaizhi WangSchool of clinical medicine, Bengbu Medical University, Bengbu, Anhui, China.
Zhenghong LiSchool of Basic Medical Sciences, Bengbu Medical University, Bengbu, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: This study aims to conduct a systematic review and meta-analysis to investigate how imaging parameters derived from Methods: A comprehensive search was conducted in PubMed, Embase, Cochrane Library, and Web of Science databases to retrieve relevant literature from their inception to December 24, 2024. This study is registered in PROSPERO (CRD42025634694). The protocol was completed in accordance with the PRISMA guidelines recommended by the EJNMMI authors' guide. Cohort studies were included that enrolled patients diagnosed with DLBCL via Results: A total of 14 studies were included, involving 1,088 patients (aged 20 to 86 years) diagnosed with DLBCL based on Conclusion: The outcomes of DLBCL cases managed using CAR-T cells can be effectively predicted using both metabolic metrics from Systematic Review Registration: https://www.crd.york.ac.uk/prospero, identifier CRD42025634694.

Indexed as

Immunotherapy, AdoptiveLymphoma, Large B-Cell, DiffusePositron Emission Tomography Computed TomographyAdultAgedAged, 80 and overFluorodeoxyglucose F18HumansMiddle AgedPrognosisTreatment OutcomeFluorodeoxyglucose F1818F-fluorodeoxyglucose positron emission tomography/computed tomographychimeric antigen receptor T-celldiffuse large B-cell lymphomameta-analysissystematic review.

Identifiers

PMID41816336
PMCPMC12971458

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.