Evidence map›Paper›PMID 41816318›Full record

ArticleInfection prevention in practice2026

Peri-operative antibiotic prophylaxis in obstetrics: a 6-year evaluation of guideline adherence and stewardship impact in a Ukrainian maternity hospital.

O Pechak, K Bielka, M Frank, H Fomina, D Yevstifeiev, L Yanitska

Abstract read
In one paragraph

Article in Infection prevention in practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

O PechakDepartment of Medical Biochemistry and Molecular Biology, Bogomolets National Medical University, Kyiv, Ukraine.
K BielkaDepartment of Surgery, Anesthesiology and Intensive Care of Postgraduate Education, Bogomolets National Medical University, Kyiv, Ukraine.
M FrankDepartment of Surgery, Anesthesiology and Intensive Care of Postgraduate Education, Bogomolets National Medical University, Kyiv, Ukraine.
H FominaDepartment of Surgery, Anesthesiology and Intensive Care of Postgraduate Education, Bogomolets National Medical University, Kyiv, Ukraine.
D YevstifeievDepartment of Medical Biochemistry and Molecular Biology, Bogomolets National Medical University, Kyiv, Ukraine.
L YanitskaDepartment of Medical Biochemistry and Molecular Biology, Bogomolets National Medical University, Kyiv, Ukraine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Surgical-site infections are a major concern in obstetric surgery. In Ukraine, evolving national guidelines and institutional antimicrobial stewardship (AMS) initiatives have sought to optimize peri-operative antibiotic prophylaxis (PAP), but their impact on clinical outcomes requires rigorous evaluation. Methods: We conducted a retrospective cohort study (2018-2023) of 474 obstetric surgeries to evaluate changes in PAP adherence and its association with length of stay (LOS). Adherence was assessed using a 3-point compliance score (timing, choice, and duration). The association between compliance and time to discharge was analysed using a multi-variable Cox proportional hazards model. Findings: A marked improvement in practice was observed; full compliance increased from 11% to 71%, while mean LOS decreased from 9.9 to 4.7 days. Component analysis showed that structural interventions eliminated duration errors, while errors in antibiotic choice persisted. In the multi-variable model, the 'year of surgery' was the strongest predictor of earlier discharge ( Conclusion: Multi-faceted AMS programs can successfully optimize PAP adherence and improve outcomes. While the overall reduction in LOS is driven by broad improvements over time, specific guideline adherence remains a crucial quality indicator, particularly for standardized procedures.

Indexed as

antimicrobial stewardshipguideline adherencehospitalizationobstetric surgeryperi-operative antibiotic prophylaxisUkraine

Identifiers

PMID41816318
PMCPMC12972720

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.