Evidence map›Paper›PMID 41816259›Full record

ArticleJournal of psoriasis and psoriatic arthritis2026

Determinants of Quality of Life and Mental Health in Kenyan Psoriasis Patients: A Cross-Sectional Analysis from the Kenyan Psoriasis Registry.

Miranda K Chen, Petronilla Biwott, Isabel Muraguri, Georgia Marquez-Grap, Gian Carlo Baldonado, Payton Smith, Toby Maurer, Tina Bhutani, Samson Kiprono, Wilson Liao

Abstract read
In one paragraph

Article in Journal of psoriasis and psoriatic arthritis, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Miranda K ChenDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID https://orcid.org/0009-0001-7115-3106
Petronilla BiwottDepartment of Medicine, Moi University, Eldoret, Kenya.
Isabel MuraguriDepartment of Medicine, Moi University, Eldoret, Kenya.
Georgia Marquez-GrapDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID https://orcid.org/0000-0002-8342-4954
Gian Carlo BaldonadoDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
Payton SmithDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
Toby MaurerDepartment of Dermatology, Indiana University, Indianapolis, IN, USA.
Tina BhutaniDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.
Samson KipronoDepartment of Medicine, Moi University, Eldoret, Kenya.
Wilson LiaoDepartment of Dermatology, University of California San Francisco, San Francisco, CA, USA.ORCID https://orcid.org/0000-0001-7883-6439

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Psoriasis is a chronic immune-mediated disease with global prevalence of 2-3% that is associated with significantly reduced quality of life (QoL) and worsened mental health. Despite this, there is a lack of research in African psoriasis populations, with no modern epidemiological studies conducted in Kenya to examine these factors. This study aims to identify demographic and clinical features associated with dermatology-related QoL and mental health among psoriasis patients enrolled in the newly established Kenyan Psoriasis Registry (KPR), based at Moi Teaching and Referral Hospital in Eldoret, Kenya. Patients and Methods: In a cross-sectional analysis of 97 adult psoriasis patients enrolled in the KPR, we evaluated associations of demographic and disease characteristics with independent outcomes of dermatology-associated QoL (Dermatology Life Quality Index, DLQI), anxiety (Generalized Anxiety Disorder 7-item, GAD-7), and depression (Patient Health Questionnaire 9-item, PHQ-9). Univariate and multivariate linear regression models were used to identify associations, with Results: In univariate analyses, age, female gender, marital status, certain subethnicities, high-impact body sites, itch and pain, sleep disturbance, and disease severity were factors associated with worse QoL, anxiety, and depression scores. In multivariate analyses, younger age, Itch Numeric Rating Scale, and Patient-Reported Outcomes Measurement Information System (PROMIS) Sleep Disturbance T-score remained significantly associated with worse DLQI. Both PROMIS Sleep Disturbance and separated marital status were associated with worse GAD-7 and PHQ-9. Conclusion: Kenyan psoriasis patients experience significant QoL and mental health burden, with younger age, itch, sleep disturbance, and separated marital status associated with worse outcomes.

Indexed as

global healthKenyamental healthpsoriasisquality of lifesleep disturbance

Identifiers

PMID41816259
PMCPMC12971513

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.