ArticleJournal of family medicine and primary care2026
Correlation between serum uric acid levels and target organ damage in apparently healthy subjects with newly diagnosed Grade I/Grade II essential hypertension: An observational cross-sectional study.
Article in Journal of family medicine and primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Hypertension is a global health issue linked to target organ damage (TOD) in the heart, kidneys, and eyes. Serum uric acid (SUA) has been proposed as a potential marker for assessing TOD in hypertensive patients. This study explored the relationship between SUA levels and TOD in individuals newly diagnosed with Grade I or II essential hypertension. Methods: Conducted at AIIMS Bhubaneswar, the study included 80 patients-40 each with Grade I and II hypertension. SUA levels were measured and correlated with: • Left ventricular diastolic dysfunction (LVDD) via 2D echocardiography, • Microalbuminuria via urine albumin-creatinine ratio (ACR), • Hypertensive retinopathy via fundoscopy. Statistical tools included Kruskal-Wallis test, Spearman's correlation, regression analysis, and ROC curve analysis. Results: SUA levels were significantly elevated in patients with advanced LVDD ( Conclusion: SUA is strongly associated with TOD in early-stage hypertension and may serve as a cost-effective biomarker for early detection of hypertensive complications. Further studies are needed to confirm these findings.
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