Evidence map›Paper›PMID 41816032›Full record

ArticleQuantitative imaging in medicine and surgery2026

Correlation between contrast-enhanced T2 fluid-attenuated inversion recovery enhancement and dynamic contrast-enhanced magnetic resonance imaging permeability in brain metastases.

Yu Zhang, Han Bao, Junjie Ye, Jiyuan Yang, Yang Lei, Junyi Li, Jia Xie, Zongfang Li

Abstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yu ZhangDepartment of Radiology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0009-0003-2354-8933
Han BaoDepartment of Radiology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0002-0919-5655
Junjie YeYunnan Population and Family Planning Institute, Kunming, China.ORCID https://orcid.org/0009-0009-6235-676X
Jiyuan YangDepartment of Radiology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0009-0005-8898-5602
Yang LeiDepartment of Radiology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0009-0002-8965-2357
Junyi LiDepartment of Radiology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0009-0000-0191-6334
Jia XieDepartment of Radiology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0009-0002-0851-5685
Zongfang LiDepartment of Radiology, The First Affiliated Hospital of Kunming Medical University, Kunming, China.ORCID https://orcid.org/0000-0002-9700-9241

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Contrast-enhanced T2 fluid-attenuated inversion recovery (CE-T2 FLAIR) and dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) provide complementary information on lesion enhancement and vascular permeability. This study aimed to assess the correlation between CE-T2 FLAIR enhancement and DCE-MRI-derived permeability parameters in brain metastases. Methods: This single-center retrospective study included 43 patients with 80 brain metastases confirmed by pathology or follow-up between January 2018 and July 2024. All patients underwent T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), T2 FLAIR, DCE-MRI, CE-T2 FLAIR, and contrast-enhanced T1WI (CE-T1WI) examinations. Quantitative DCE-MRI parameters were evaluated for all lesions, including the volume transfer constant (K Results: Groups A, B, and C included 17, 45, and 18 lesions, respectively. Group A showed significantly higher CR and PI and lower K Conclusions: Vascular permeability of brain metastases is a key factor contributing to the differential enhancement observed between CE-T2 FLAIR and CE-T1WI, with CE-T2 FLAIR demonstrating superior sensitivity in detecting metastases with low vascular permeability.

Indexed as

Brain metastasesdynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)fluid-attenuated inversion recovery sequence (FLAIR sequence)magnetic resonance imaging (MRI)

Identifiers

PMID41816032
PMCPMC12971330

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